Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KIF11 | P52732 | 1/20 | 0.33 |
| ▸ | ESR1 | P03372 | 1/20 | 0.32 |
| ▸ | ADH1B | P00325 | 1/20 | 0.30 |
| ▸ | ADH1C | P00326 | 1/20 | 0.30 |
| ▸ | ADH1A | P07327 | 1/20 | 0.30 |
| ▸ | ADH7 | P40394 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8892088 | 0.88 | KIF11 (0.35) | KIF11ESR1ADH1BADH1CADH1A | |
| SCHEMBL7817328 | 0.85 | ADH1B (0.38) | KIF11ADH1BADH1CADH1AADH7 | |
| SCHEMBL7827162 | 0.81 | ADH1B (0.37) | ADH1BADH1CADH1AADH7 | |
| SCHEMBL7830286 | 0.78 | KIF11 (0.39) | KIF11 | |
| SCHEMBL7817246 | 0.76 | ADH1B (0.37) | ADH1BADH1CADH1AADH7 | |
| SCHEMBL8894063 | 0.76 | ADH1B (0.37) | ADH1BADH1CADH1AADH7 | |
| SCHEMBL7823967 | 0.75 | KIF11 (0.43) | KIF11 | |
| Hydrochloric Acid SCHEMBL7459726 | 0.71 | CCR3 (0.61) | — | |
| SCHEMBL7823386 | 0.71 | ADH1B (0.38) | ADH1BADH1CADH1AADH7 | |
| SCHEMBL7822809 | 0.70 | CCR3 (0.37) | ADH1BADH1CADH1AADH7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1997024325-A1 | DIPHENYLMETHANE DERIVATIVES AS MIP-1α/RANTES RECEPTOR ANTAGONISTS | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1997-07-10 | — | — | WO | disclosed |