Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADH1B | P00325 | 1/20 | 0.37 |
| ▸ | ADH1C | P00326 | 1/20 | 0.37 |
| ▸ | ADH1A | P07327 | 1/20 | 0.37 |
| ▸ | ADH7 | P40394 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | MAOA | P21397 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8894063 | 0.94 | ADH1B (0.37) | ADH1BADH1CADH1AADH7ALDH1A1 | |
| SCHEMBL7817328 | 0.86 | ADH1B (0.38) | ADH1BADH1CADH1AADH7ALDH1A1 | |
| SCHEMBL7832303 | 0.84 | CCR1 (0.37) | ADH1BADH1CADH1AADH7ALDH1A1 | |
| SCHEMBL7827162 | 0.81 | ADH1B (0.37) | ADH1BADH1CADH1AADH7ALDH1A1 | |
| SCHEMBL7830286 | 0.79 | KIF11 (0.39) | MEN1KMT2A | |
| SCHEMBL8892870 | 0.78 | CCR1 (0.37) | ADH1BADH1CADH1AADH7ALDH1A1 | |
| SCHEMBL7823967 | 0.76 | KIF11 (0.43) | ALDH1A1MEN1KMT2A | |
| SCHEMBL8892472 | 0.76 | KIF11 (0.33) | ADH1BADH1CADH1AADH7 | |
| SCHEMBL7824371 | 0.73 | L3MBTL1 (0.48) | — | |
| SCHEMBL4454569 | 0.71 | TAAR1 (0.44) | ADH1BADH1CADH1AADH7ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0712845-B1 | Amine compounds, their production and use | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 2001-10-17 | — | — | EP | disclosed |
| WO-1997024325-A1 | DIPHENYLMETHANE DERIVATIVES AS MIP-1α/RANTES RECEPTOR ANTAGONISTS | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1997-07-10 | — | — | WO | disclosed |
| US-5633248-A | GONADOTROPIN-RELEASING HORMONE RECEPTOR ANTAGONISTS, DIARYLALKYLIDENEDIAMINES | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1997-05-27 | — | — | US | disclosed |
| EP-0712845-A1 | Amine compounds, their production and use | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1996-05-22 | — | — | EP | disclosed |