SCHEMBL8892495

SCHEMBL8892495

Cc1nc(NC(=O)OC(C)(C)C)c(S(=O)(=O)c2ccccc2)o1

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.45
MAPT P10636 2/20 0.45
KDM4E B2RXH2 2/20 0.45
NPSR1 Q6W5P4 2/20 0.40
MEN1 O00255 3/20 0.38
KMT2A Q03164 3/20 0.38
NPC1 O15118 2/20 0.38
RAB9A P51151 2/20 0.38
GAA P10253 1/20 0.38
CA12 O43570 1/20 0.38
CA1 P00915 1/20 0.38
CA7 P43166 1/20 0.38
CA14 Q9ULX7 1/20 0.38
ELANE P08246 1/20 0.38
CTRB1 P17538 1/20 0.38
ATM Q13315 1/20 0.37
LMNA P02545 2/20 0.37
BCHE P06276 1/20 0.36
ABCC9 O60706 1/20 0.36
ABCC8 Q09428 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8890670 0.71 ALDH1A1 (0.52) ALDH1A1MAPTKDM4ENPSR1MEN1
SCHEMBL8892158 0.68 ALDH1A1 (0.49) ALDH1A1MAPTKDM4EMEN1KMT2A
SCHEMBL5394506 0.66 CA1 (0.57) ALDH1A1KDM4EGAACA12CA1
SCHEMBL7079519 0.65 MEN1 (0.58) ALDH1A1MAPTNPSR1MEN1KMT2A
SCHEMBL7079521 0.65 SMN1; SMN2 (0.52) ALDH1A1KDM4EMEN1KMT2AGAA
SCHEMBL775002 0.65 NAMPT (0.56) ALDH1A1MEN1KMT2ANPC1RAB9A
SCHEMBL362443 0.65 CA1 (0.36) ALDH1A1MAPTNPSR1MEN1KMT2A
SCHEMBL20865568 0.65 LMNA (0.57) MAPTGAACA1LMNASMN1; SMN2
Toluene SCHEMBL28585498 0.65 CA12 (0.52) ALDH1A1GAACA12CA1CA7
SCHEMBL2880194 0.64 BRD9 (0.52) ALDH1A1MEN1KMT2ANPC1RAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-1997024340-A1 OXAZOLE DERIVATIVES, THEIR PRODUCTION AND USE TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) 1997-07-10 WO disclosed