Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 3/20 | 0.42 |
| ▸ | KCNA3 | P22001 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | DRD2 | P14416 | 1/20 | 0.37 |
| ▸ | DRD4 | P21917 | 1/20 | 0.37 |
| ▸ | DRD3 | P35462 | 1/20 | 0.37 |
| ▸ | CCR1 | P32246 | 1/20 | 0.37 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.36 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | KIF11 | P52732 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7826967 | 0.86 | KCNA3 (0.52) | OPRM1KCNA3SMN1; SMN2POLBCYP2D6 | |
| SCHEMBL7828708 | 0.80 | OPRM1 (0.47) | OPRM1KCNA3SMN1; SMN2POLBCYP2D6 | |
| SCHEMBL8314746 | 0.80 | OPRM1 (0.47) | OPRM1KCNA3SMN1; SMN2POLBKDM4E | |
| SCHEMBL7830375 | 0.79 | OPRM1 (0.50) | OPRM1KCNA3SMN1; SMN2POLBALDH1A1 | |
| SCHEMBL7824585 | 0.79 | OPRM1 (0.46) | OPRM1KCNA3SMN1; SMN2POLBALDH1A1 | |
| SCHEMBL8046235 | 0.78 | OPRM1 (0.49) | OPRM1KCNA3SMN1; SMN2POLBALDH1A1 | |
| SCHEMBL5751743 | 0.78 | KDM4E (0.40) | KDM4EALDH1A1CYP4F2CYP4A11NPSR1 | |
| SCHEMBL8891230 | 0.77 | SMN1; SMN2 (0.43) | OPRM1KCNA3SMN1; SMN2POLBKDM4E | |
| SCHEMBL8311559 | 0.77 | OPRM1 (0.49) | OPRM1KCNA3SMN1; SMN2POLBALDH1A1 | |
| SCHEMBL8049892 | 0.77 | OPRM1 (0.48) | OPRM1KCNA3SMN1; SMN2POLBALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1997024325-A1 | DIPHENYLMETHANE DERIVATIVES AS MIP-1α/RANTES RECEPTOR ANTAGONISTS | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1997-07-10 | — | — | WO | disclosed |