Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 11/20 | 0.53 |
| ▸ | THRA | P10827 | 9/20 | 0.53 |
| ▸ | RORC | P51449 | 2/20 | 0.52 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8893247 | 0.87 | THRB (0.57) | THRBTHRARORCCYP2D6 | |
| SCHEMBL3886566 | 0.84 | THRB (0.57) | THRBTHRARORC | |
| SCHEMBL5618523 | 0.82 | THRB (0.53) | THRBTHRARORCCYP2D6 | |
| SCHEMBL7071121 | 0.82 | THRB (0.55) | THRBTHRARORC | |
| SCHEMBL16496567 | 0.82 | THRB (0.53) | THRBTHRARORC | |
| SCHEMBL7076989 | 0.82 | THRB (0.73) | THRBTHRARORC | |
| SCHEMBL2788081 | 0.81 | THRB (0.73) | THRBTHRARORC | |
| SCHEMBL7073367 | 0.81 | THRB (0.56) | THRBTHRARORCCYP2D6 | |
| SCHEMBL7054452 | 0.80 | THRB (0.57) | THRBTHRARORC | |
| SCHEMBL5618520 | 0.80 | THRB (0.53) | THRBTHRARORCCYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5654468-A | ANTILIPID, ANTICHOLESTEROL AGENTS | CIBA-GEIGY CORPORATION (US) | 1997-08-05 | — | — | US | disclosed |
| US-5569674-A | ANTICHOLESTEROL AGENTS | CIBA-GEIGY CORPORATION (US) | 1996-10-29 | — | — | US | disclosed |
| US-5401772-A | Anticholesterol agents with aromatic amines | CIBA-GEIGY CORPORATION (US) | 1995-03-28 | — | — | US | disclosed |