Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 5/20 | 0.44 |
| ▸ | ITGA2B | P08514 | 5/20 | 0.44 |
| ▸ | F10 | P00742 | 2/20 | 0.44 |
| ▸ | RBP4 | P02753 | 1/20 | 0.37 |
| ▸ | HRH1 | P35367 | 1/20 | 0.37 |
| ▸ | CCR3 | P51677 | 1/20 | 0.37 |
| ▸ | PLA2G2A | P14555 | 3/20 | 0.35 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | DPP4 | P27487 | 1/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.33 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.33 |
| ▸ | ADH5 | P11766 | 1/20 | 0.33 |
| ▸ | CETP | P11597 | 2/20 | 0.33 |
| ▸ | RARB | P10826 | 1/20 | 0.32 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.32 |
| ▸ | NPBWR1 | P48145 | 1/20 | 0.32 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8891636 | 0.92 | ITGB3 (0.42) | ITGB3ITGA2BF10RBP4HRH1 | |
| SCHEMBL8894165 | 0.89 | ITGB3 (0.46) | ITGB3ITGA2BF10RBP4HRH1 | |
| SCHEMBL7457519 | 0.88 | ITGB3 (0.43) | ITGB3ITGA2BF10RBP4HRH1 | |
| SCHEMBL8891846 | 0.86 | ITGB3 (0.48) | ITGB3ITGA2BF10RBP4HRH1 | |
| SCHEMBL8891474 | 0.82 | PLA2G2A (0.44) | ITGB3ITGA2BF10RBP4PLA2G2A | |
| SCHEMBL8894310 | 0.82 | GPR119 (0.36) | ITGB3ITGA2BF10GPR119NPBWR1 | |
| SCHEMBL8892720 | 0.81 | GPR119 (0.42) | GPR119CETP | |
| SCHEMBL8892934 | 0.80 | ITGB3 (0.43) | ITGB3ITGA2BF10GPR119 | |
| SCHEMBL8892671 | 0.80 | ITGB3 (0.49) | ITGB3ITGA2BF10RBP4HRH1 | |
| SCHEMBL8892115 | 0.79 | NAMPT (0.37) | F10GPR119ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5614535-A | Adhesion receptor antagonists | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1997-03-25 | — | — | US | disclosed |