Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 6/20 | 0.49 |
| ▸ | ITGA2B | P08514 | 6/20 | 0.49 |
| ▸ | F10 | P00742 | 3/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | PLA2G2A | P14555 | 4/20 | 0.39 |
| ▸ | CMA1 | P23946 | 1/20 | 0.35 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.35 |
| ▸ | HRH1 | P35367 | 1/20 | 0.35 |
| ▸ | CCR3 | P51677 | 1/20 | 0.35 |
| ▸ | ADH5 | P11766 | 1/20 | 0.35 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.34 |
| ▸ | SMYD3 | Q9H7B4 | 1/20 | 0.34 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.34 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.34 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | RBP4 | P02753 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8894165 | 0.89 | ITGB3 (0.46) | ITGB3ITGA2BF10ALDH1A1PLA2G2A | |
| SCHEMBL8892595 | 0.80 | ITGB3 (0.44) | ITGB3ITGA2BF10ALDH1A1PLA2G2A | |
| SCHEMBL8891846 | 0.80 | ITGB3 (0.48) | ITGB3ITGA2BF10ALDH1A1PLA2G2A | |
| SCHEMBL8891947 | 0.79 | ITGB3 (0.53) | ITGB3ITGA2BF10PRSS1PRSS2 | |
| SCHEMBL7457519 | 0.79 | ITGB3 (0.43) | ITGB3ITGA2BF10ALDH1A1PLA2G2A | |
| SCHEMBL8894032 | 0.77 | ITGB3 (0.45) | ITGB3ITGA2BF10PLA2G2AADH5 | |
| SCHEMBL8891474 | 0.76 | PLA2G2A (0.44) | ITGB3ITGA2BF10ALDH1A1PLA2G2A | |
| SCHEMBL7461428 | 0.76 | ITGB3 (0.44) | ITGB3ITGA2BF10ALDH1A1PLA2G2A | |
| SCHEMBL8891636 | 0.75 | ITGB3 (0.42) | ITGB3ITGA2BF10ALDH1A1PLA2G2A | |
| SCHEMBL8893341 | 0.75 | ITGB3 (0.56) | ITGB3ITGA2BF10ALDH1A1PLA2G2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5614535-A | Adhesion receptor antagonists | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1997-03-25 | — | — | US | disclosed |