Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 1/20 | 0.38 |
| ▸ | CA9 | Q16790 | 1/20 | 0.38 |
| ▸ | GRIN2D | O15399 | 2/20 | 0.37 |
| ▸ | GRIN3B | O60391 | 2/20 | 0.37 |
| ▸ | GRIN1 | Q05586 | 2/20 | 0.37 |
| ▸ | GRIN2A | Q12879 | 2/20 | 0.37 |
| ▸ | GRIN2B | Q13224 | 2/20 | 0.37 |
| ▸ | GRIN2C | Q14957 | 2/20 | 0.37 |
| ▸ | GRIN3A | Q8TCU5 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | BLM | P54132 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8901336 | 0.76 | GRIA1 (0.35) | KMT2AGRIA1GRIA2GRIA4GRIK5 | |
| SCHEMBL639581 | 0.75 | DAO (0.55) | PGRPTGDR2MDM2 | |
| SCHEMBL8893031 | 0.72 | GRIN2D (0.48) | CA12CA9GRIN2DGRIN3BGRIN1 | |
| SCHEMBL8892597 | 0.68 | KDM4E (0.43) | CA12CA9GRIN1GRIN2BMEN1 | |
| SCHEMBL10487991 | 0.67 | ALDH1A1 (0.46) | GRIN1GRIN2BMEN1CYP2D6CYP2C9 | |
| SCHEMBL27524563 | 0.65 | CSNK2A2 (0.37) | MEN1CYP1A2CYP2C19BLMKMT2A | |
| SCHEMBL6526383 | 0.65 | CSNK2A2 (0.37) | MEN1CYP1A2CYP2C19BLMKMT2A | |
| SCHEMBL8893965 | 0.61 | PTGDR2 (0.43) | TSHRPTGDR2 | |
| SCHEMBL7336986 | 0.61 | KDM4E (0.45) | MEN1CYP1A2TSHRKMT2A | |
| SCHEMBL25335125 | 0.60 | ALDH1A1 (0.55) | CA12CA9MEN1CYP1A2HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1997002254-A1 | QUINAZOLINE DERIVATIVES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1997-01-23 | — | — | WO | disclosed |