Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 5/20 | 0.56 |
| ▸ | ITGA2B | P08514 | 5/20 | 0.56 |
| ▸ | F10 | P00742 | 2/20 | 0.56 |
| ▸ | ADH5 | P11766 | 1/20 | 0.47 |
| ▸ | XDH | P47989 | 2/20 | 0.41 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | PLA2G2A | P14555 | 3/20 | 0.39 |
| ▸ | PARP1 | P09874 | 1/20 | 0.38 |
| ▸ | RARB | P10826 | 1/20 | 0.38 |
| ▸ | RBP4 | P02753 | 1/20 | 0.37 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.37 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.37 |
| ▸ | RARA | P10276 | 1/20 | 0.37 |
| ▸ | CCKBR | P32239 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7463090 | 0.83 | ITGB3 (0.53) | ITGB3ITGA2BF10ADH5XDH | |
| SCHEMBL8892944 | 0.83 | ITGB3 (0.49) | ITGB3ITGA2BF10ADH5XDH | |
| SCHEMBL7461633 | 0.83 | ITGB3 (0.51) | ITGB3ITGA2BF10ADH5XDH | |
| SCHEMBL8892462 | 0.81 | ITGB3 (0.49) | ITGB3ITGA2BF10ADH5XDH | |
| SCHEMBL6606264 | 0.81 | ITGB3 (0.58) | ITGB3ITGA2BF10ADH5ALDH1A1 | |
| SCHEMBL7460284 | 0.80 | ITGB3 (0.46) | ITGB3ITGA2BF10ADH5XDH | |
| SCHEMBL7456647 | 0.79 | ITGB3 (0.49) | ITGB3ITGA2BF10ADH5XDH | |
| SCHEMBL8892492 | 0.78 | ITGB3 (0.49) | ITGB3ITGA2BF10ADH5XDH | |
| SCHEMBL7468374 | 0.77 | ITGB3 (0.43) | ITGB3ITGA2BF10ADH5XDH | |
| SCHEMBL8891846 | 0.76 | ITGB3 (0.48) | ITGB3ITGA2BF10ADH5ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5614535-A | Adhesion receptor antagonists | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1997-03-25 | — | — | US | disclosed |