Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PGK1 | P00558 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 3/20 | 0.43 |
| ▸ | GALR2 | O43603 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | GLP1R | P43220 | 2/20 | 0.43 |
| ▸ | CCR2 | P41597 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.35 |
| ▸ | RXFP1 | Q9HBX9 | 7/20 | 0.34 |
| ▸ | MAPT | P10636 | 3/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | GLA | P06280 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8893491 | 0.87 | PGK1 (0.59) | PGK1POLBGALR2LMNAGLP1R | |
| SCHEMBL8892240 | 0.84 | PDE7A (0.51) | PGK1POLBGALR2LMNAGLP1R | |
| SCHEMBL8893038 | 0.84 | POLB (0.47) | PGK1POLBGALR2LMNAGLP1R | |
| SCHEMBL8917176 | 0.83 | PGK1 (0.47) | PGK1POLBGALR2LMNAGLP1R | |
| SCHEMBL8892065 | 0.82 | PGK1 (0.39) | PGK1POLBGALR2LMNAGLP1R | |
| SCHEMBL8891980 | 0.82 | POLB (0.46) | PGK1POLBGALR2LMNAGLP1R | |
| SCHEMBL8891999 | 0.81 | POLB (0.43) | PGK1POLBGALR2LMNAGLP1R | |
| SCHEMBL8891651 | 0.77 | LMNA (0.40) | PGK1POLBGALR2LMNAGLP1R | |
| SCHEMBL8892306 | 0.76 | GUCY1B2 (0.50) | POLBLMNAALDH1A1SMN1; SMN2MEN1 | |
| Hydrochloric Acid SCHEMBL8891535 | 0.74 | LMNA (0.44) | POLBLMNAALDH1A1SMN1; SMN2KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1997032858-A1 | QUINOXALINE DERIVATIVES AS GLUTAMATE RECEPTOR ANTAGONISTS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1997-09-12 | — | — | WO | disclosed |