Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PGK1 | P00558 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 3/20 | 0.45 |
| ▸ | POLB | P06746 | 3/20 | 0.45 |
| ▸ | GALR2 | O43603 | 1/20 | 0.45 |
| ▸ | GRM6 | O15303 | 1/20 | 0.37 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.37 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.37 |
| ▸ | GRIA3 | P42263 | 1/20 | 0.37 |
| ▸ | GRIA4 | P48058 | 1/20 | 0.37 |
| ▸ | PDE7A | Q13946 | 4/20 | 0.37 |
| ▸ | PDE7B | Q9NP56 | 2/20 | 0.37 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.37 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 4/20 | 0.37 |
| ▸ | HTT | P42858 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | GLP1R | P43220 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | APEX1 | P27695 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8892839 | 0.83 | PGK1 (0.45) | PGK1LMNAPOLBGALR2MAPT | |
| SCHEMBL31530747 | 0.82 | LMNA (0.57) | PGK1LMNAPOLBGALR2GRM6 | |
| SCHEMBL31530748 | 0.82 | LMNA (0.57) | PGK1LMNAPOLBGALR2GRM6 | |
| SCHEMBL8552936 | 0.82 | LMNA (0.57) | PGK1LMNAPOLBGALR2GRM6 | |
| SCHEMBL1291907 | 0.80 | PGK1 (0.61) | PGK1LMNAPOLBGALR2GRM6 | |
| SCHEMBL8556955 | 0.77 | GAA (0.51) | PGK1LMNAPOLBGALR2GRM6 | |
| SCHEMBL6370768 | 0.77 | PDE7A (0.53) | PGK1PDE7APDE7BPDE4BPDE4D | |
| SCHEMBL5722727 | 0.74 | POLB (0.44) | PGK1LMNAPOLBGALR2GRM6 | |
| SCHEMBL8893002 | 0.73 | POLB (0.45) | PGK1LMNAPOLBGALR2GRM6 | |
| SCHEMBL5722662 | 0.73 | PDE7A (0.36) | PGK1LMNAPOLBGALR2PDE7A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1997032858-A1 | QUINOXALINE DERIVATIVES AS GLUTAMATE RECEPTOR ANTAGONISTS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1997-09-12 | — | — | WO | disclosed |