Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 5/20 | 0.49 |
| ▸ | ITGA2B | P08514 | 5/20 | 0.49 |
| ▸ | F10 | P00742 | 2/20 | 0.49 |
| ▸ | ADH5 | P11766 | 1/20 | 0.40 |
| ▸ | XDH | P47989 | 2/20 | 0.37 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.37 |
| ▸ | RARA | P10276 | 1/20 | 0.36 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | CCKBR | P32239 | 2/20 | 0.35 |
| ▸ | DPP4 | P27487 | 1/20 | 0.35 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.35 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7460284 | 0.91 | ITGB3 (0.46) | ITGB3ITGA2BF10ADH5XDH | |
| SCHEMBL7468374 | 0.87 | ITGB3 (0.43) | ITGB3ITGA2BF10ADH5XDH | |
| SCHEMBL8893341 | 0.83 | ITGB3 (0.56) | ITGB3ITGA2BF10ADH5XDH | |
| SCHEMBL8892492 | 0.82 | ITGB3 (0.49) | ITGB3ITGA2BF10ADH5XDH | |
| SCHEMBL8892912 | 0.81 | ADORA2A (0.50) | ITGB3ITGA2BF10ALDH1A1 | |
| SCHEMBL7463090 | 0.81 | ITGB3 (0.53) | ITGB3ITGA2BF10ADH5XDH | |
| SCHEMBL7457540 | 0.76 | ITGB3 (0.44) | ITGB3ITGA2BF10 | |
| SCHEMBL7452003 | 0.76 | ITGB3 (0.46) | ITGB3ITGA2BF10 | |
| SCHEMBL7460203 | 0.75 | ITGB3 (0.43) | ITGB3ITGA2BF10ALDH1A1 | |
| SCHEMBL7461633 | 0.74 | ITGB3 (0.51) | ITGB3ITGA2BF10ADH5XDH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5614535-A | Adhesion receptor antagonists | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1997-03-25 | — | — | US | disclosed |