SCHEMBL8893024

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL19371262	0.88	ALDH1A1 (0.46)	HPDMEN1KMT2APKMALDH1A1
	SCHEMBL19371255	0.86	MAPT (0.45)	HPDMEN1KMT2APKMALDH1A1
	SCHEMBL6072863	0.84	HPD (0.50)	HPDMEN1KMT2APKMALDH1A1
	SCHEMBL21219021	0.83	ALDH1A1 (0.53)	HPDMEN1KMT2APKMALDH1A1
	SCHEMBL25296472	0.82	KMT2A (0.41)	MEN1KMT2APKMALDH1A1MAPT
	SCHEMBL3124584	0.82	VCAM1 (0.45)	MEN1KMT2APKMALDH1A1MAPT
	SCHEMBL4093917	0.82	VCAM1 (0.45)	MEN1KMT2APKMALDH1A1MAPT
	SCHEMBL16695369	0.82	PDE2A (0.51)	MEN1KMT2AALDH1A1CYP1A2CYP2C19
	SCHEMBL3834152	0.82	MAPT (0.45)	HPDMEN1KMT2APKMALDH1A1
	SCHEMBL997304	0.81	ALDH1A1 (0.49)	HPDMEN1KMT2APKMALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.