Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.44 |
| ▸ | HPD | P32754 | 3/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.42 |
| ▸ | GAA | P10253 | 2/20 | 0.42 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | KCNMA1 | Q12791 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19742873 | 0.90 | FLT1 (0.40) | MAPTCYP3A4CYP1A2CYP2D6CYP2C9 | |
| SCHEMBL21219021 | 0.88 | ALDH1A1 (0.53) | MAPTCYP3A4CYP1A2CYP2C19ALDH1A1 | |
| SCHEMBL19371262 | 0.84 | ALDH1A1 (0.46) | MAPTCYP3A4CYP1A2CYP2C19ALDH1A1 | |
| SCHEMBL3831033 | 0.83 | TDP1 (0.41) | MAPTMAPK1LMNAKCNMA1TDP1 | |
| SCHEMBL7056432 | 0.82 | MEN1 (0.41) | MAPTCYP3A4CYP1A2CYP2D6CYP2C9 | |
| SCHEMBL8893024 | 0.82 | HPD (0.46) | MAPTCYP3A4CYP1A2CYP2C19ALDH1A1 | |
| SCHEMBL19371255 | 0.82 | MAPT (0.45) | MAPTCYP3A4CYP2C9CYP2C19ALDH1A1 | |
| SCHEMBL7059291 | 0.80 | ALDH1A1 (0.53) | MAPTCYP3A4CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL3836060 | 0.80 | TSHR (0.46) | MAPTCYP3A4ALDH1A1MEN1KMT2A | |
| SCHEMBL3207172 | 0.80 | S100A4 (0.37) | MAPTCYP1A2ALDH1A1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3222606-B1 | CARBOXYLIC ACID PREPARATION METHOD | ZHEJIANG ZHUJI UNITED CHEMICALS CO LTD (CN) | 2019-08-07 | — | — | EP | claimed |
| US-10167246-B2 | Preparative method for carboxylic acids | ZHEJIANG ZHUJI UNITED CHEMICALS CO., LTD (CN) | 2019-01-01 | — | — | US | claimed |
| US-20170369412-A1 | Preparative method for carboxylic acids | ZHEJIANG ZHUJI UNITED CHEMICALS CO., LTD | 2017-12-28 | — | — | US | claimed |
| EP-3222606-A1 | CARBOXYLIC ACID PREPARATION METHOD | Zhejiang Zhuji United Chemicals Co., Ltd (CN) | 2017-09-27 | — | — | EP | claimed |
| EP-3222606-B1 | CARBOXYLIC ACID PREPARATION METHOD | ZHEJIANG ZHUJI UNITED CHEMICALS CO LTD (CN) | 2019-08-07 | — | — | EP | disclosed |
| US-10167246-B2 | Preparative method for carboxylic acids | ZHEJIANG ZHUJI UNITED CHEMICALS CO., LTD (CN) | 2019-01-01 | — | — | US | disclosed |
| US-20170369412-A1 | Preparative method for carboxylic acids | ZHEJIANG ZHUJI UNITED CHEMICALS CO., LTD | 2017-12-28 | — | — | US | disclosed |
| EP-3222606-A1 | CARBOXYLIC ACID PREPARATION METHOD | Zhejiang Zhuji United Chemicals Co., Ltd (CN) | 2017-09-27 | — | — | EP | disclosed |
| EP-2119703-B1 | NOVEL INDOLE DERIVATIVE HAVING INHIBITORY ACTIVITY ON I B KINASE | SANTEN PHARMACEUTICAL CO LTD (JP) | 2012-12-12 | — | — | EP | disclosed |
| US-8193237-B2 | Indole derivative having IκB kinase β inhibitory activity | SANTEN PHARMACEUTICAL CO., LTD. (JP) | 2012-06-05 | — | — | US | disclosed |
| US-20100041628-A1 | NOVEL INDOLE DERIVATIVE HAVING IKAPPAB KINASE BETA INHIBITORY ACTIVITY | SANTEN PHARMACEUTICAL CO., LTD. (JP) | 2010-02-18 | — | — | US | disclosed |
| EP-2119703-A1 | NOVEL INDOLE DERIVATIVE HAVING INHIBITORY ACTIVITY ON I B KINASE | Santen Pharmaceutical Co., Ltd (JP) | 2009-11-18 | — | — | EP | disclosed |
| EP-2119703-A1 | NOVEL INDOLE DERIVATIVE HAVING INHIBITORY ACTIVITY ON I B KINASE | Santen Pharmaceutical Co., Ltd (JP) | 2009-11-18 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100041628-A1 | NOVEL INDOLE DERIVATIVE HAVING IKAPPAB KINASE BETA INHIBITORY ACTIVITY | NFKBIA, IKBKB, IKBKG | MAPT 3915/4885CYP3A4 4790/4885CYP1A2 4686/4885 |
| US-20170369412-A1 | Preparative method for carboxylic acids | CBR3, CBR1, QPCT | MAPT 4862/4885CYP3A4 491/4885CYP1A2 581/4885 |
| US-10167246-B2 | Preparative method for carboxylic acids | CBR3, CBR1, QPCT | MAPT 4862/4885CYP3A4 491/4885CYP1A2 581/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.