SCHEMBL8893075

SCHEMBL8893075

C=CCN(CC=C)CCC1CCNCC1

nearest known ligand 0.31

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
HRH3 Q9Y5N1 1/20 0.31
BRD4 O60885 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL8925165 0.80 LSS (0.34) BRD4
SCHEMBL3999956 0.74 GNAO1 (0.39) HRH3BRD4
SCHEMBL9676330 0.73 SLC6A1 (0.37) HRH3
SCHEMBL5261715 0.73 HRH3 (0.35) HRH3
SCHEMBL5178457 0.72 GBA1 (0.35) HRH3BRD4
SCHEMBL20072734 0.72 HRH3 (0.33) HRH3BRD4
Hydrochloric Acid SCHEMBL6147160 0.72 GNAO1 (0.41) HRH3BRD4
Hydrochloric Acid SCHEMBL31392340 0.71 GNAO1 (0.36) HRH3
Hydrochloric Acid SCHEMBL5179835 0.71 GBA1 (0.34) HRH3BRD4
SCHEMBL9674095 0.70 CYP2D6 (0.31) HRH3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-1997043292-A1 NEW THIAZOLOPYRIDINES KLINGE PHARMA GMBH (DE) 1997-11-20 WO disclosed