Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GBA1 | P04062 | 3/20 | 0.35 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.33 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.33 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.33 |
| ▸ | BRD4 | O60885 | 1/20 | 0.32 |
| ▸ | ITGB3 | P05106 | 2/20 | 0.32 |
| ▸ | ITGA2B | P08514 | 2/20 | 0.32 |
| ▸ | LSS | P48449 | 1/20 | 0.32 |
| ▸ | SLC6A1 | P30531 | 2/20 | 0.31 |
| ▸ | GABRA5 | P31644 | 2/20 | 0.31 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.31 |
| ▸ | SLC6A12 | P48065 | 2/20 | 0.31 |
| ▸ | SLC6A11 | P48066 | 2/20 | 0.31 |
| ▸ | SLC6A13 | Q9NSD5 | 2/20 | 0.31 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.31 |
| ▸ | GABRR1 | P24046 | 1/20 | 0.31 |
| ▸ | GABRA4 | P48169 | 1/20 | 0.31 |
| ▸ | GNAO1 | P09471 | 3/20 | 0.31 |
| ▸ | CPN1 | P15169 | 1/20 | 0.31 |
| ▸ | CPB2 | Q96IY4 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL5179835 | 0.98 | GBA1 (0.34) | GBA1SLC6A2SLC6A4HRH3BRD4 | |
| SCHEMBL5180771 | 0.81 | GBA1 (0.36) | GBA1SLC6A2SLC6A4SLC6A1GABRA5 | |
| SCHEMBL18970796 | 0.80 | CYP1A2 (0.36) | LSS | |
| SCHEMBL21540719 | 0.80 | BRD4 (0.36) | GBA1SLC6A2SLC6A4HRH3BRD4 | |
| SCHEMBL20072734 | 0.79 | HRH3 (0.33) | GBA1HRH3BRD4GNAO1 | |
| SCHEMBL28281 | 0.77 | — | — | |
| SCHEMBL3999956 | 0.77 | GNAO1 (0.39) | GBA1SLC6A2SLC6A4HRH3BRD4 | |
| Trolamine SCHEMBL11407288 | 0.77 | MAPT (0.38) | — | |
| Hydrochloric Acid SCHEMBL6147160 | 0.75 | GNAO1 (0.41) | GBA1SLC6A2SLC6A4HRH3BRD4 | |
| SCHEMBL28134700 | 0.75 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0927174-B1 | NEW AMINO ALCOHOL DERIVATIVES, PROCESS FOR THE PRODUCTION THEREOF AND MEDICAMENTS AND REAGENTS CONTAINING THESE COMPOUNDS | MEDIGENE AG (DE) | 2007-12-12 | — | — | EP | disclosed |
| US-7097854-B2 | Amino alcohol derivatives, process for their production and pharmaceutical preparations and reagents containing these compounds | MEDIGENE ONCOLOGY GMBH (DE) | 2006-08-29 | — | — | US | disclosed |
| US-20030236266-A1 | Amino alcohol derivatives, process for their production and pharmaceutical preparations and reagents containing these compounds | ROCHE DIAGNOSTICS GMBH | 2003-12-25 | — | — | US | disclosed |
| CN-1087293-C | New amino alcohol derivatives, process for production thereof and medicaments and reagents containing these compounds | ROHER DIAGNOSTIC EQUIPMENT AG (DE) | 2002-07-10 | — | — | CN | disclosed |
| CN-1237161-A | New amino alcohol derivatives, process for production thereof and medicaments and reagents containing these compounds | ROHER DIAGNOSTIC EQUIPMENT AG (DE) | 1999-12-01 | — | — | CN | disclosed |
| EP-0927174-A1 | NEW AMINO ALCOHOL DERIVATIVES, PROCESS FOR THE PRODUCTION THEREOF AND MEDICAMENTS AND REAGENTS CONTAINING THESE COMPOUNDS | MediGene Oncology GmbH (DE) | 1999-07-07 | — | — | EP | disclosed |
| WO-1998011082-A1 | NEW AMINO ALCOHOL DERIVATIVES, PROCESS FOR THE PRODUCTION THEREOF AND MEDICAMENTS AND REAGENTS CONTAINING THESE COMPOUNDS | ROCHE DIAGNOSTICS GMBH (DE) | 1998-03-19 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030236266-A1 | Amino alcohol derivatives, process for their production and pharmaceutical preparations and reagents containing these compounds | ADH1C, ADH1A, ADH5 | GBA1 4431/4885SLC6A2 1354/4885SLC6A4 1867/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.