Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.33 |
| ▸ | BRD4 | O60885 | 1/20 | 0.32 |
| ▸ | GNAO1 | P09471 | 1/20 | 0.31 |
| ▸ | GBA1 | P04062 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5178457 | 0.79 | GBA1 (0.35) | HRH3BRD4GNAO1GBA1 | |
| SCHEMBL20063315 | 0.78 | SIGMAR1 (0.50) | — | |
| Hydrochloric Acid SCHEMBL5179835 | 0.78 | GBA1 (0.34) | HRH3BRD4GNAO1GBA1 | |
| SCHEMBL331464 | 0.77 | — | — | |
| SCHEMBL3999956 | 0.77 | GNAO1 (0.39) | HRH3BRD4GNAO1GBA1 | |
| Hydrochloric Acid SCHEMBL6147160 | 0.75 | GNAO1 (0.41) | HRH3BRD4GNAO1GBA1 | |
| Hydrochloric Acid SCHEMBL1082281 | 0.75 | GNAO1 (0.39) | HRH3GNAO1GBA1 | |
| Hydrochloric Acid SCHEMBL3666386 | 0.75 | GNAO1 (0.39) | HRH3GNAO1GBA1 | |
| SCHEMBL19720087 | 0.75 | GNAI3 (0.31) | GNAO1 | |
| SCHEMBL19032594 | 0.73 | GNAO1 (0.51) | GNAO1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180104342-A1 | LIPID COMPOSITIONS | ARBUTUS BIOPHARMA CORPORATION (CA) | 2018-04-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180104342-A1 | LIPID COMPOSITIONS | SGMS1, LIPA, SGMS2 | HRH3 3127/4885BRD4 4779/4885GNAO1 2037/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.