SCHEMBL8893096

SCHEMBL8893096

CCCC[CH]C(=O)OC(C)c1ccccc1

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HCAR2 Q8TDS4 1/20 0.56
CYP1A2 P05177 8/20 0.43
CYP2C9 P11712 7/20 0.43
TSHR P16473 7/20 0.43
CYP2C19 P33261 7/20 0.43
CYP3A4 P08684 6/20 0.43
ALDH1A1 P00352 6/20 0.43
CYP2D6 P10635 4/20 0.42
SMN1; SMN2 Q16637 4/20 0.42
LMNA P02545 2/20 0.42
POLB P06746 1/20 0.41
MAPK1 P28482 1/20 0.41
CTSK P43235 3/20 0.40
ASAH1 Q13510 1/20 0.39
ACER2 Q5QJU3 1/20 0.39
NAAA Q02083 2/20 0.38
KDM4E B2RXH2 1/20 0.38
HSD17B10 Q99714 1/20 0.38
LTB4R Q15722 1/20 0.38
LTB4R2 Q9NPC1 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8894250 0.95 HCAR2 (0.55) HCAR2CYP1A2CYP2C9TSHRCYP2C19
SCHEMBL8895081 0.94 HCAR2 (0.54) HCAR2ALDH1A1SMN1; SMN2LMNAPOLB
SCHEMBL8896300 0.94 HCAR2 (0.54) HCAR2ALDH1A1SMN1; SMN2LMNAPOLB
SCHEMBL8896104 0.94 HCAR2 (0.54) HCAR2ALDH1A1SMN1; SMN2LMNAPOLB
SCHEMBL8894632 0.94 HCAR2 (0.54) HCAR2ALDH1A1SMN1; SMN2LMNAPOLB
SCHEMBL8894006 0.91 HCAR2 (0.59) HCAR2CYP1A2CYP2C9TSHRCYP2C19
SCHEMBL8894982 0.84 HCAR2 (0.63) HCAR2CYP1A2TSHRALDH1A1CYP2D6
SCHEMBL11039134 0.82 NAAA (0.41) HCAR2CYP1A2CYP2C9TSHRCYP2C19
SCHEMBL8894289 0.79 ZDHHC2 (0.39) CYP1A2CYP2C9TSHRCYP2C19CYP3A4
SCHEMBL8895942 0.78 ALDH1A1 (0.39) CYP1A2CYP2C9TSHRCYP2C19CYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5670563-A ORGANOTIN COMPOUND, PHOSPHORUS COMPOUND CIBA-SPECIALTY CHEMICALS CORPORATION (US) 1997-09-23 US disclosed