Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | ASAH1 | Q13510 | 2/20 | 0.43 |
| ▸ | ACER2 | Q5QJU3 | 1/20 | 0.43 |
| ▸ | NAAA | Q02083 | 2/20 | 0.43 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | SOAT2 | O75908 | 1/20 | 0.41 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | CYSLTR2 | Q9NS75 | 2/20 | 0.39 |
| ▸ | CYSLTR1 | Q9Y271 | 2/20 | 0.39 |
| ▸ | ZDHHC2 | Q9UIJ5 | 1/20 | 0.39 |
| ▸ | FAAH | O00519 | 1/20 | 0.39 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8896104 | 1.00 | HCAR2 (0.54) | HCAR2ALDH1A1ASAH1ACER2NAAA | |
| SCHEMBL8896300 | 1.00 | HCAR2 (0.54) | HCAR2ALDH1A1ASAH1ACER2NAAA | |
| SCHEMBL8894632 | 1.00 | HCAR2 (0.54) | HCAR2ALDH1A1ASAH1ACER2NAAA | |
| SCHEMBL8894250 | 0.99 | HCAR2 (0.55) | HCAR2ALDH1A1ASAH1ACER2NAAA | |
| SCHEMBL8893096 | 0.94 | HCAR2 (0.56) | HCAR2ALDH1A1ASAH1ACER2NAAA | |
| SCHEMBL8894006 | 0.88 | HCAR2 (0.59) | HCAR2ALDH1A1POLB | |
| SCHEMBL11039134 | 0.85 | NAAA (0.41) | HCAR2ALDH1A1ASAH1ACER2NAAA | |
| SCHEMBL8896106 | 0.84 | NAAA (0.42) | ALDH1A1ASAH1ACER2NAAANPC1 | |
| SCHEMBL8895942 | 0.82 | ALDH1A1 (0.39) | ALDH1A1ASAH1ACER2NAAANPC1 | |
| SCHEMBL8894982 | 0.82 | HCAR2 (0.63) | HCAR2ALDH1A1SMN1; SMN2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5670563-A | ORGANOTIN COMPOUND, PHOSPHORUS COMPOUND | CIBA-SPECIALTY CHEMICALS CORPORATION (US) | 1997-09-23 | — | — | US | disclosed |