Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | ASAH1 | Q13510 | 2/20 | 0.41 |
| ▸ | ACER2 | Q5QJU3 | 1/20 | 0.41 |
| ▸ | NAAA | Q02083 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.40 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | CTSK | P43235 | 3/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.39 |
| ▸ | TSHR | P16473 | 3/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.39 |
| ▸ | SOAT2 | O75908 | 1/20 | 0.39 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8895081 | 0.99 | HCAR2 (0.54) | HCAR2ALDH1A1ASAH1ACER2NAAA | |
| SCHEMBL8896104 | 0.99 | HCAR2 (0.54) | HCAR2ALDH1A1ASAH1ACER2NAAA | |
| SCHEMBL8894632 | 0.99 | HCAR2 (0.54) | HCAR2ALDH1A1ASAH1ACER2NAAA | |
| SCHEMBL8896300 | 0.99 | HCAR2 (0.54) | HCAR2ALDH1A1ASAH1ACER2NAAA | |
| SCHEMBL8893096 | 0.95 | HCAR2 (0.56) | HCAR2ALDH1A1ASAH1ACER2NAAA | |
| SCHEMBL8894006 | 0.89 | HCAR2 (0.59) | HCAR2ALDH1A1POLBCYP1A2CYP3A4 | |
| SCHEMBL11039134 | 0.87 | NAAA (0.41) | HCAR2ALDH1A1ASAH1ACER2NAAA | |
| SCHEMBL8895942 | 0.83 | ALDH1A1 (0.39) | ALDH1A1ASAH1ACER2NAAAPOLB | |
| SCHEMBL8896106 | 0.83 | NAAA (0.42) | ALDH1A1ASAH1ACER2NAAASMN1; SMN2 | |
| SCHEMBL8894982 | 0.83 | HCAR2 (0.63) | HCAR2ALDH1A1SMN1; SMN2LMNACYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5670563-A | ORGANOTIN COMPOUND, PHOSPHORUS COMPOUND | CIBA-SPECIALTY CHEMICALS CORPORATION (US) | 1997-09-23 | — | — | US | disclosed |