Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TBXA2R | P21731 | 6/20 | 0.37 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.35 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | HPGD | P15428 | 2/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | S1PR2 | O95136 | 1/20 | 0.33 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.33 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.33 |
| ▸ | PTGDR | Q13258 | 5/20 | 0.33 |
| ▸ | PTGDR2 | Q9Y5Y4 | 3/20 | 0.33 |
| ▸ | PDE4A | P27815 | 1/20 | 0.33 |
| ▸ | TSPO | P30536 | 1/20 | 0.33 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.33 |
| ▸ | DRD3 | P35462 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8891580 | 0.90 | PTGS1 (0.35) | TBXA2RPTGS1PTGS2PTGDR2PDE2A | |
| SCHEMBL8890836 | 0.90 | TAS1R3 (0.33) | PTGS2ALDH1A1PTGDR2PDE2A | |
| SCHEMBL8892787 | 0.87 | HPGD (0.36) | ALDH1A1KDM4EHPGDCYP1A2CYP3A4 | |
| SCHEMBL8891456 | 0.85 | ALDH1A1 (0.35) | ALDH1A1KDM4EHPGDCYP1A2CYP3A4 | |
| SCHEMBL8892550 | 0.84 | ALDH1A1 (0.34) | ALDH1A1KDM4EHPGDCYP1A2CYP3A4 | |
| SCHEMBL8890301 | 0.83 | TAS1R3 (0.33) | HPGDCYP1A2CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL9069510 | 0.83 | DHODH (0.36) | PDE2A | |
| SCHEMBL9069529 | 0.82 | DHODH (0.34) | PDE2A | |
| SCHEMBL123795 | 0.82 | F10 (0.39) | HPGDPDE2ASLC6A9 | |
| SCHEMBL8489076 | 0.82 | DHODH (0.35) | PTGS1PTGS2PDE2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1997028136-A1 | BENZOYLISOXAZOLES AND 2-CYANO-1,3-DIONE DERIVATIVES AND THEIR USE AS HERBICIDES | RHONE-POULENC AGRICULTURE LTD. (GB) | 1997-08-07 | — | — | WO | disclosed |