Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.33 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.33 |
| ▸ | TAS1R2 | Q8TE23 | 1/20 | 0.33 |
| ▸ | MAP2K1 | Q02750 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | ATM | Q13315 | 1/20 | 0.32 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.32 |
| ▸ | CCR5 | P51681 | 1/20 | 0.32 |
| ▸ | BRD4 | O60885 | 2/20 | 0.31 |
| ▸ | PDE2A | O00408 | 1/20 | 0.31 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.31 |
| ▸ | PLA2G2A | P14555 | 3/20 | 0.31 |
| ▸ | DHODH | Q02127 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8890836 | 0.93 | TAS1R3 (0.33) | TAS1R3TAS1R1TAS1R2MAP2K1PTGDR2 | |
| SCHEMBL8891643 | 0.87 | CCR5 (0.35) | TAS1R3TAS1R1TAS1R2MAP2K1PTGDR2 | |
| SCHEMBL8891005 | 0.85 | PLA2G2A (0.36) | TAS1R3TAS1R1TAS1R2MAP2K1PTGDR2 | |
| SCHEMBL8891039 | 0.83 | TAS1R3 (0.34) | TAS1R3TAS1R1TAS1R2MAP2K1PTGDR2 | |
| SCHEMBL8891638 | 0.83 | ALOX15 (0.36) | TAS1R3TAS1R1TAS1R2MAP2K1HPGD | |
| SCHEMBL8891580 | 0.83 | PTGS1 (0.35) | PTGDR2PDE2ADHODH | |
| SCHEMBL8893301 | 0.83 | TBXA2R (0.37) | CYP1A2CYP3A4CYP2D6CYP2C9HPGD | |
| SCHEMBL8890676 | 0.83 | ALDH1A1 (0.35) | TAS1R3TAS1R1TAS1R2MAP2K1HPGD | |
| SCHEMBL8489199 | 0.82 | NAAA (0.38) | TAS1R3TAS1R1TAS1R2MAPTPDE2A | |
| SCHEMBL8891827 | 0.82 | LMNA (0.36) | TAS1R3TAS1R1TAS1R2CCR5DHODH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1997028136-A1 | BENZOYLISOXAZOLES AND 2-CYANO-1,3-DIONE DERIVATIVES AND THEIR USE AS HERBICIDES | RHONE-POULENC AGRICULTURE LTD. (GB) | 1997-08-07 | — | — | WO | disclosed |