Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 5/20 | 0.58 |
| ▸ | ITGA2B | P08514 | 5/20 | 0.58 |
| ▸ | F10 | P00742 | 2/20 | 0.58 |
| ▸ | CALML3 | P27482 | 6/20 | 0.49 |
| ▸ | MAOA | P21397 | 2/20 | 0.47 |
| ▸ | MAOB | P27338 | 2/20 | 0.47 |
| ▸ | ADH5 | P11766 | 1/20 | 0.44 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7230274 | 0.85 | ITGB3 (0.54) | ITGB3ITGA2BF10ADH5GRM2 | |
| SCHEMBL7316619 | 0.82 | ITGB3 (0.51) | ITGB3ITGA2BF10ADH5GRM2 | |
| SCHEMBL8893341 | 0.81 | ITGB3 (0.56) | ITGB3ITGA2BF10ADH5ALDH1A1 | |
| SCHEMBL7461633 | 0.78 | ITGB3 (0.51) | ITGB3ITGA2BF10ADH5ALDH1A1 | |
| SCHEMBL9550251 | 0.77 | MAOA (0.59) | CALML3MAOAMAOBGRM2 | |
| SCHEMBL5639142 | 0.76 | CALML3 (0.51) | CALML3MAOAMAOBGRM2 | |
| SCHEMBL7307485 | 0.75 | MAOA (0.52) | CALML3MAOAMAOBGRM2 | |
| SCHEMBL9549439 | 0.75 | GRM2 (0.64) | F10CALML3MAOAMAOBGRM2 | |
| SCHEMBL9482302 | 0.75 | GRM2 (0.64) | F10CALML3MAOAMAOBGRM2 | |
| SCHEMBL12603742 | 0.75 | ADH5 (0.56) | ITGB3ITGA2BF10ADH5ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0741133-B1 | Adhesion receptor antagonists | MERCK PATENT GMBH (DE) | 2004-01-28 | — | — | EP | disclosed |
| US-5627197-A | Adhesion receptor antagonists | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1997-05-06 | — | — | US | disclosed |
| EP-0741133-A2 | Adhesion receptor antagonists | MERCK PATENT GmbH (DE) | 1996-11-06 | — | — | EP | disclosed |
| EP-0727425-A1 | Adhesion receptor antagonists | MERCK PATENT GmbH (DE) | 1996-08-21 | — | — | EP | disclosed |