Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | LTA4H | P09960 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.33 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.33 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.33 |
| ▸ | HTR2A | P28223 | 1/20 | 0.33 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.33 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.33 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.33 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.32 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8893116 | 0.98 | MEN1 (0.36) | MEN1KMT2AHPGDLTA4HALDH1A1 | |
| SCHEMBL8895729 | 0.89 | L3MBTL1 (0.34) | MEN1KMT2AHPGDLTA4HALDH1A1 | |
| SCHEMBL8896038 | 0.88 | ALDH1A1 (0.34) | MEN1KMT2AHPGDALDH1A1LMNA | |
| SCHEMBL8893220 | 0.86 | ALDH1A1 (0.33) | MEN1KMT2AHPGDALDH1A1LMNA | |
| SCHEMBL8893928 | 0.82 | ABCB1 (0.40) | MEN1KMT2ALTA4HALDH1A1LMNA | |
| SCHEMBL3050396 | 0.78 | KMT2A (0.49) | MEN1KMT2AHPGDLTA4HALDH1A1 | |
| SCHEMBL3474010 | 0.78 | LTA4H (0.35) | KMT2AHPGDLTA4HALDH1A1 | |
| SCHEMBL8707727 | 0.78 | ABCB1 (0.41) | MEN1KMT2AALDH1A1LMNAPOLB | |
| SCHEMBL8894248 | 0.78 | ALDH1A1 (0.32) | MEN1KMT2AALDH1A1LMNAPOLB | |
| SCHEMBL8894581 | 0.76 | MEN1 (0.42) | MEN1KMT2AHPGDALDH1A1ADRA2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5624897-A | PARASITICIDES, NEMATOSIDES OF CYCLIC PEPTIDE LACTONES FOR VETERINARY MEDICINE | BAYER AKTIENGESELLSCHAFT (DE) | 1997-04-29 | — | — | US | disclosed |