SCHEMBL8896038

SCHEMBL8896038

CC(O)CCC[C@H](C)[C@@H](C(=O)CC(O)C(=O)OC(C)(C)C)N(C)C(=O)[C@H](C)N(C)Cc1ccccc1

nearest known ligand 0.34

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.34
MEN1 O00255 3/20 0.33
KMT2A Q03164 3/20 0.33
HCRTR1 O43613 1/20 0.33
CHRNB2 P17787 1/20 0.32
CHRNB4 P30926 1/20 0.32
CHRNA3 P32297 1/20 0.32
CHRNA4 P43681 1/20 0.32
KLK5 Q9Y337 1/20 0.32
AKT1 P31749 2/20 0.32
KDM4E B2RXH2 1/20 0.32
ATM Q13315 1/20 0.32
LMNA P02545 1/20 0.32
POLB P06746 1/20 0.32
HSD17B10 Q99714 1/20 0.32
L3MBTL1 Q9Y468 1/20 0.32
HPGD P15428 1/20 0.31
CTSL P07711 1/20 0.31
CTSB P07858 1/20 0.31
CTSS P25774 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8893220 0.98 ALDH1A1 (0.33) ALDH1A1MEN1KMT2AHCRTR1CHRNB2
SCHEMBL8894248 0.90 ALDH1A1 (0.32) ALDH1A1MEN1KMT2AHCRTR1CHRNB2
SCHEMBL8893427 0.88 MEN1 (0.37) ALDH1A1MEN1KMT2ACHRNB2CHRNB4
SCHEMBL8892974 0.86 ABCB1 (0.37) POLBL3MBTL1CTSLCTSBCTSS
SCHEMBL8893116 0.86 MEN1 (0.36) ALDH1A1MEN1KMT2ACHRNB2CHRNB4
SCHEMBL8714486 0.82 ABCB1 (0.38) MEN1KMT2APOLBL3MBTL1CTSL
SCHEMBL8893949 0.82 ABCB1 (0.38) MEN1KMT2APOLBL3MBTL1CTSL
SCHEMBL8895474 0.81 MEN1 (0.43) ALDH1A1MEN1KMT2AHCRTR1CHRNB2
SCHEMBL8895202 0.79 ALDH1A1 (0.38) ALDH1A1MEN1KMT2AHCRTR1CHRNB2
SCHEMBL8894255 0.78

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5624897-A PARASITICIDES, NEMATOSIDES OF CYCLIC PEPTIDE LACTONES FOR VETERINARY MEDICINE BAYER AKTIENGESELLSCHAFT (DE) 1997-04-29 US disclosed