SCHEMBL8893483

SCHEMBL8893483

Brc1nccnc1-c1ccccc1

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALOX15 P16050 1/20 0.41
DCLK1 O15075 1/20 0.40
PRKD3 O94806 1/20 0.40
MAP4K4 O95819 1/20 0.40
CHEK2 O96017 1/20 0.40
CSF1R P07333 1/20 0.40
FER P16591 1/20 0.40
CDK2 P24941 1/20 0.40
MARK3 P27448 1/20 0.40
FLT4 P35916 1/20 0.40
FLT3 P36888 1/20 0.40
MAPK9 P45984 1/20 0.40
CSNK1D P48730 1/20 0.40
CLK2 P49760 1/20 0.40
CSNK2A1 P68400 1/20 0.40
CSNK1G2 P78368 1/20 0.40
MAP4K2 Q12851 1/20 0.40
STK3 Q13188 1/20 0.40
CAMK2B Q13554 1/20 0.40
CAMK2G Q13555 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL460510 0.82 ALOX15 (0.50) ALOX15SLC22A12HTR2BHTR5ATDO2
SCHEMBL27664892 0.82 ALOX15 (0.50) ALOX15SLC22A12HTR2BHTR5ATDO2
SCHEMBL30021764 0.79 ALOX15 (0.48) ALOX15SLC22A12HTR2BHTR5ATDO2
Hydrochloric Acid SCHEMBL4703144 0.79 ALOX15 (0.48) ALOX15SLC22A12HTR2BHTR5ATDO2
SCHEMBL28601515 0.78 HSD17B1 (0.42) KDM4ECYP3A4MAPTNPC1RAB9A
SCHEMBL31051290 0.77 PDE3B (0.41) PRKD3MAP4K4MAPK9CSNK1DPRKD2
SCHEMBL27766178 0.77 PDE3B (0.41) TDO2KDM4EMAPTALDH1A1NOTUM
SCHEMBL14525924 0.77 ALDH1A1 (0.50) ALOX15SLC22A12HTR2BHTR5ATDO2
SCHEMBL14525863 0.77 ALDH1A1 (0.50) ALOX15SLC22A12HTR2BHTR5ATDO2
SCHEMBL1683247 0.76 HTR2B (0.40) ALOX15DCLK1PRKD3MAP4K4CHEK2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-104649961-B Luminescent layer material of main part and organic electroluminescence device 固安鼎材科技有限公司 2017-09-19 CN disclosed
CN-104649961-A 2,6,6,8-tetra-substituted-6H-benzo[cd]pyrene compounds and organic light emitting device containing same BEIJING ETERNAL MATERIAL TECHNOLOGY CO LTD 2015-05-27 CN disclosed
US-5626791-A FERROELECTRIC LIQUID CRYSTALS HOECHST AKTIENGESELLSCHAFT (DE) 1997-05-06 US disclosed