Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KIF11 | P52732 | 8/20 | 0.44 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.44 |
| ▸ | GRM2 | Q14416 | 2/20 | 0.43 |
| ▸ | GRM3 | Q14832 | 2/20 | 0.43 |
| ▸ | LTA4H | P09960 | 1/20 | 0.41 |
| ▸ | AAK1 | Q2M2I8 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9544124 | 0.87 | GRM2 (0.49) | KIF11SLC7A5GRM2GRM3LTA4H | |
| SCHEMBL7319980 | 0.87 | GRM2 (0.49) | KIF11SLC7A5GRM2GRM3LTA4H | |
| SCHEMBL28271058 | 0.82 | AAK1 (0.44) | AAK1 | |
| SCHEMBL2291108 | 0.82 | CTSK (0.44) | AAK1 | |
| SCHEMBL28022205 | 0.82 | AAK1 (0.44) | AAK1 | |
| SCHEMBL28124091 | 0.81 | CTSK (0.41) | LTA4HAAK1 | |
| SCHEMBL17079753 | 0.81 | LTA4H (0.42) | KIF11SLC7A5GRM2GRM3LTA4H | |
| Ammonia Solution, Strong SCHEMBL28118901 | 0.81 | AAK1 (0.43) | AAK1 | |
| SCHEMBL27590205 | 0.81 | AAK1 (0.39) | GRM2GRM3LTA4HAAK1 | |
| SCHEMBL15268712 | 0.80 | SLC6A2 (0.42) | AAK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5663148-A | ANTIINFLAMMATORY AGENTS OF OLIGOPEPTIDES FOR BACTERICIDES, FUNGICIDES, ANTICARCINOGENIC AGENTS, VIRICIDES OR AUTOIMMUNE DISEASES | ABBOTT LABORATORIES (US) | 1997-09-02 | — | — | US | disclosed |
| WO-1994007815-A2 | SMALL PEPTIDE ANAPHYLATOXIN RECEPTOR LIGANDS | ABBOTT LABORATORIES (US) | 1994-04-14 | — | — | WO | disclosed |