Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM2 | Q14416 | 2/20 | 0.49 |
| ▸ | GRM3 | Q14832 | 2/20 | 0.49 |
| ▸ | SLC7A5 | Q01650 | 2/20 | 0.45 |
| ▸ | KIF11 | P52732 | 2/20 | 0.42 |
| ▸ | SLC1A1 | P43005 | 3/20 | 0.42 |
| ▸ | SLC1A2 | P43004 | 2/20 | 0.42 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.42 |
| ▸ | KYNU | Q16719 | 1/20 | 0.41 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.41 |
| ▸ | ALPI | P09923 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.40 |
| ▸ | XIAP | P98170 | 1/20 | 0.40 |
| ▸ | LTA4H | P09960 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9544124 | 1.00 | GRM2 (0.49) | GRM2GRM3SLC7A5KIF11SLC1A1 | |
| SCHEMBL17079753 | 0.88 | LTA4H (0.42) | GRM2GRM3SLC7A5KIF11LTA4H | |
| SCHEMBL8893618 | 0.87 | KIF11 (0.44) | GRM2GRM3SLC7A5KIF11LTA4H | |
| SCHEMBL6704315 | 0.87 | AAK1 (0.39) | PKMLTA4H | |
| SCHEMBL28356651 | 0.87 | AAK1 (0.39) | PKMLTA4H | |
| SCHEMBL28750863 | 0.85 | AAK1 (0.39) | SLC7A5PKMLTA4H | |
| SCHEMBL15268712 | 0.81 | SLC6A2 (0.42) | PKM | |
| SCHEMBL2293652 | 0.80 | MEN1 (0.55) | — | |
| SCHEMBL6448129 | 0.79 | GRM2 (0.62) | GRM2GRM3SLC7A5SLC1A1SLC1A2 | |
| SCHEMBL5286288 | 0.79 | GRM2 (0.62) | GRM2GRM3SLC7A5SLC1A1SLC1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0119705-B1 | OCTAPEPTIDE VASOPRESSIN ANTAGONISTS | SMITHKLINE BECKMAN CORPORATION (US) | 1989-09-06 | — | — | EP | disclosed |
| US-4684622-A | CYCLIC OLIGOPEPTIDES, DISULFIDE LINKAGE | SMITHKLINE BECKMAN CORPORATION (US) | 1987-08-04 | — | — | US | disclosed |
| US-4599324-A | VASODILATORS | SMITHKLINE BECKMAN CORPORATION (US) | 1986-07-08 | — | — | US | disclosed |
| EP-0182626-A2 | V1-vasopressin antagonists | SMITHKLINE BECKMAN CORPORATION (US) | 1986-05-28 | — | — | EP | disclosed |
| US-4587045-A | Intermediates for preparing octapeptide vasopressin antagonists | SMITHKLINE BECKMAN CORPORATION (US) | 1986-05-06 | — | — | US | disclosed |
| US-4542124-A | Octapeptide vasopressin antagonists | SMITHKLINE BECKMAN CORPORATION (US) | 1985-09-17 | — | — | US | disclosed |
| EP-0119705-A2 | Octapeptide vasopressin antagonists | SMITHKLINE BECKMAN CORPORATION (US) | 1984-09-26 | — | — | EP | disclosed |
| US-4469679-A | DIURETICS | SMITHKLINE BECKMAN CORPORATION (US) | 1984-09-04 | — | — | US | disclosed |