Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 4/20 | 0.46 |
| ▸ | DRD3 | P35462 | 4/20 | 0.46 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | FNTA | P49354 | 2/20 | 0.44 |
| ▸ | FNTB | P49356 | 2/20 | 0.44 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.43 |
| ▸ | FAAH | O00519 | 3/20 | 0.41 |
| ▸ | TACR1 | P25103 | 1/20 | 0.40 |
| ▸ | ICMT | O60725 | 1/20 | 0.40 |
| ▸ | DRD4 | P21917 | 2/20 | 0.40 |
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.39 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.39 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | BCHE | P06276 | 1/20 | 0.38 |
| ▸ | ACHE | P22303 | 1/20 | 0.38 |
| ▸ | HTR1A | P08908 | 1/20 | 0.38 |
| ▸ | HTR1D | P28221 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8784611 | 0.92 | FNTA (0.46) | DRD2DRD3OPRK1KDM4EFNTA | |
| SCHEMBL8895210 | 0.92 | FNTA (0.44) | DRD2DRD3OPRK1FNTAFNTB | |
| SCHEMBL8548651 | 0.91 | DRD2 (0.47) | DRD2DRD3OPRK1FNTAFNTB | |
| SCHEMBL8783305 | 0.91 | DRD2 (0.47) | DRD2DRD3OPRK1FNTAFNTB | |
| SCHEMBL8956646 | 0.91 | DRD2 (0.47) | DRD2DRD3OPRK1FNTAFNTB | |
| SCHEMBL8957016 | 0.88 | TACR1 (0.54) | DRD2DRD3OPRK1KDM4EFNTA | |
| SCHEMBL9245521 | 0.88 | TACR1 (0.54) | DRD2DRD3OPRK1KDM4EFNTA | |
| SCHEMBL9142783 | 0.84 | FNTA (0.60) | KDM4EFNTAFNTBSIGMAR1TACR1 | |
| SCHEMBL8783447 | 0.81 | FNTA (0.53) | KDM4EFNTAFNTBSIGMAR1TACR1 | |
| SCHEMBL8895688 | 0.81 | FNTA (0.51) | OPRK1KDM4EFNTAFNTBTACR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5631279-A | ANTAGONISTS OF NEUROKININ A | RHONE-POULENC RORER, S.A. (FR) | 1997-05-20 | — | — | US | disclosed |