Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FNTA | P49354 | 5/20 | 0.44 |
| ▸ | FNTB | P49356 | 5/20 | 0.44 |
| ▸ | TACR1 | P25103 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.40 |
| ▸ | ICMT | O60725 | 1/20 | 0.40 |
| ▸ | DRD2 | P14416 | 2/20 | 0.39 |
| ▸ | DRD3 | P35462 | 2/20 | 0.39 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.38 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.38 |
| ▸ | HTR1A | P08908 | 1/20 | 0.38 |
| ▸ | HTR7 | P34969 | 1/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 3/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8893638 | 0.92 | DRD2 (0.46) | FNTAFNTBTACR1OPRK1ICMT | |
| SCHEMBL8784611 | 0.92 | FNTA (0.46) | FNTAFNTBTACR1TSHROPRK1 | |
| SCHEMBL8783305 | 0.91 | DRD2 (0.47) | FNTAFNTBTACR1OPRK1DRD2 | |
| SCHEMBL8956646 | 0.91 | DRD2 (0.47) | FNTAFNTBTACR1OPRK1DRD2 | |
| SCHEMBL8548651 | 0.91 | DRD2 (0.47) | FNTAFNTBTACR1OPRK1DRD2 | |
| SCHEMBL8956827 | 0.88 | TACR1 (0.55) | FNTAFNTBTACR1TSHROPRK1 | |
| SCHEMBL9243104 | 0.88 | TACR1 (0.55) | FNTAFNTBTACR1TSHROPRK1 | |
| SCHEMBL9142783 | 0.84 | FNTA (0.60) | FNTAFNTBTACR1TSHRMEN1 | |
| SCHEMBL9245521 | 0.81 | TACR1 (0.54) | FNTAFNTBTACR1OPRK1ICMT | |
| SCHEMBL8957016 | 0.81 | TACR1 (0.54) | FNTAFNTBTACR1OPRK1ICMT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5631279-A | ANTAGONISTS OF NEUROKININ A | RHONE-POULENC RORER, S.A. (FR) | 1997-05-20 | — | — | US | disclosed |