Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.36 |
| ▸ | NPC1 | O15118 | 4/20 | 0.36 |
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7458984 | 0.89 | SMN1; SMN2 (0.32) | SMN1; SMN2NPC1RAB9ACYP2C19ALDH1A1 | |
| SCHEMBL8891713 | 0.87 | KMT2A (0.32) | HPGDSMN1; SMN2NPC1RAB9AMEN1 | |
| SCHEMBL8893748 | 0.77 | HPGD (0.44) | HPGDSMN1; SMN2NPC1RAB9AMAPT | |
| SCHEMBL8894267 | 0.74 | PRSS1 (0.51) | HPGDSMN1; SMN2NPC1RAB9ACYP2C19 | |
| SCHEMBL8892667 | 0.73 | HPGD (0.37) | HPGDSMN1; SMN2NPC1RAB9AMAPT | |
| SCHEMBL8890920 | 0.73 | L3MBTL1 (0.49) | HPGDSMN1; SMN2NPC1RAB9AMAPT | |
| SCHEMBL8893351 | 0.72 | HPGD (0.37) | HPGDSMN1; SMN2NPC1RAB9AMAPT | |
| SCHEMBL8892948 | 0.72 | SMN1; SMN2 (0.44) | HPGDSMN1; SMN2NPC1RAB9AMAPT | |
| SCHEMBL8892614 | 0.71 | HPGD (0.43) | HPGDSMN1; SMN2CYP2C19MEN1KMT2A | |
| SCHEMBL8893356 | 0.71 | SMN1; SMN2 (0.42) | HPGDSMN1; SMN2NPC1RAB9AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5614535-A | Adhesion receptor antagonists | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1997-03-25 | — | — | US | disclosed |