Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.38 |
| ▸ | FNTA | P49354 | 2/20 | 0.38 |
| ▸ | FNTB | P49356 | 2/20 | 0.38 |
| ▸ | PGGT1B | P53609 | 2/20 | 0.38 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.37 |
| ▸ | CTSL | P07711 | 1/20 | 0.37 |
| ▸ | CTSB | P07858 | 1/20 | 0.37 |
| ▸ | CTSK | P43235 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7517993 | 0.88 | L3MBTL1 (0.40) | L3MBTL1SMN1; SMN2NPC1RAB9AGRM2 | |
| SCHEMBL8893356 | 0.85 | SMN1; SMN2 (0.42) | HPGDSMN1; SMN2NPC1RAB9ACYP2C19 | |
| SCHEMBL8894267 | 0.85 | PRSS1 (0.51) | HPGDSMN1; SMN2NPC1RAB9ACYP2C19 | |
| SCHEMBL8892948 | 0.85 | SMN1; SMN2 (0.44) | HPGDSMN1; SMN2NPC1RAB9ACYP2C19 | |
| SCHEMBL8891751 | 0.85 | FNTA (0.45) | L3MBTL1GRM2POLBFNTAFNTB | |
| SCHEMBL8948663 | 0.84 | L3MBTL1 (0.49) | L3MBTL1HPGDGRM2CHRM4 | |
| SCHEMBL8948589 | 0.84 | L3MBTL1 (0.49) | L3MBTL1HPGDGRM2CHRM4 | |
| SCHEMBL8948720 | 0.84 | L3MBTL1 (0.49) | L3MBTL1HPGDGRM2CHRM4 | |
| SCHEMBL8893748 | 0.83 | HPGD (0.44) | HPGDSMN1; SMN2NPC1RAB9ACYP2C19 | |
| SCHEMBL8892614 | 0.80 | HPGD (0.43) | HPGDSMN1; SMN2CYP2C19CTSL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1204889-C | Adhesion receptor antagonists | MERCK PATENT GMBH (DE) | 2005-06-08 | — | — | CN | disclosed |
| US-5614535-A | Adhesion receptor antagonists | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1997-03-25 | — | — | US | disclosed |
| CN-1125575-A | Adhesion receptor antagonists | MERCK PATENT GMBH (DE) | 1996-07-03 | — | — | CN | disclosed |