Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | F10 | P00742 | 8/20 | 0.42 |
| ▸ | ITGB3 | P05106 | 7/20 | 0.42 |
| ▸ | PRSS1 | P07477 | 7/20 | 0.42 |
| ▸ | PRSS2 | P07478 | 7/20 | 0.42 |
| ▸ | ITGA2B | P08514 | 7/20 | 0.42 |
| ▸ | PRSS3 | P35030 | 7/20 | 0.42 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | F2 | P00734 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.36 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.36 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.36 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.36 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.36 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8894267 | 0.91 | PRSS1 (0.51) | SMN1; SMN2CYP2C19HPGDF10ITGB3 | |
| SCHEMBL8893356 | 0.90 | SMN1; SMN2 (0.42) | SMN1; SMN2CYP2C19HPGDF10ITGB3 | |
| SCHEMBL7466571 | 0.88 | SMN1; SMN2 (0.38) | SMN1; SMN2CYP2C19HPGDF10ITGB3 | |
| SCHEMBL8893748 | 0.85 | HPGD (0.44) | SMN1; SMN2CYP2C19HPGDF10ITGB3 | |
| SCHEMBL8893028 | 0.85 | ITGB3 (0.43) | SMN1; SMN2CYP2C19HPGDITGB3ITGA2B | |
| SCHEMBL8890920 | 0.85 | L3MBTL1 (0.49) | SMN1; SMN2CYP2C19HPGDNPC1RAB9A | |
| SCHEMBL8892614 | 0.80 | HPGD (0.43) | SMN1; SMN2CYP2C19HPGDF10ITGB3 | |
| SCHEMBL7462601 | 0.79 | PRSS1 (0.41) | SMN1; SMN2CYP2C19F10ITGB3PRSS1 | |
| SCHEMBL8892077 | 0.77 | ITGB3 (0.43) | HPGDF10ITGB3PRSS1PRSS2 | |
| SCHEMBL8893347 | 0.76 | SMN1; SMN2 (0.39) | SMN1; SMN2CYP2C19HPGDF10NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5614535-A | Adhesion receptor antagonists | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1997-03-25 | — | — | US | disclosed |