Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | ITGB3 | P05106 | 10/20 | 0.41 |
| ▸ | ITGA2B | P08514 | 10/20 | 0.41 |
| ▸ | F10 | P00742 | 10/20 | 0.41 |
| ▸ | PRSS1 | P07477 | 9/20 | 0.41 |
| ▸ | PRSS2 | P07478 | 9/20 | 0.41 |
| ▸ | PRSS3 | P35030 | 9/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | F2 | P00734 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8894267 | 0.90 | PRSS1 (0.51) | SMN1; SMN2CYP2C19HPGDITGB3ITGA2B | |
| SCHEMBL8892948 | 0.90 | SMN1; SMN2 (0.44) | SMN1; SMN2CYP2C19HPGDITGB3ITGA2B | |
| SCHEMBL8890920 | 0.85 | L3MBTL1 (0.49) | SMN1; SMN2CYP2C19HPGDNPC1RAB9A | |
| SCHEMBL8894588 | 0.85 | ITGB3 (0.42) | SMN1; SMN2ITGB3ITGA2BF10PRSS1 | |
| SCHEMBL8893748 | 0.84 | HPGD (0.44) | SMN1; SMN2CYP2C19HPGDITGB3ITGA2B | |
| SCHEMBL8893365 | 0.78 | SMN1; SMN2 (0.39) | SMN1; SMN2CYP2C19HPGDF10NPC1 | |
| SCHEMBL8893347 | 0.78 | SMN1; SMN2 (0.39) | SMN1; SMN2CYP2C19HPGDF10NPC1 | |
| SCHEMBL8892614 | 0.78 | HPGD (0.43) | SMN1; SMN2CYP2C19HPGDITGB3ITGA2B | |
| SCHEMBL7462601 | 0.78 | PRSS1 (0.41) | SMN1; SMN2CYP2C19ITGB3ITGA2BF10 | |
| SCHEMBL7466571 | 0.78 | SMN1; SMN2 (0.38) | SMN1; SMN2CYP2C19HPGDITGB3ITGA2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5614535-A | Adhesion receptor antagonists | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1997-03-25 | — | — | US | disclosed |