SCHEMBL8893788

SCHEMBL8893788

CC[C@H](C)[C@H](NC)C(=O)CC(O)C(=O)OC(C)(C)C

nearest known ligand 0.40

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
CTSS P25774 1/20 0.40
CTSK P43235 1/20 0.40
PSENEN Q9NZ42 1/20 0.34
CYP2D6 P10635 1/20 0.33
CA2 P00918 1/20 0.32
ALDH1A1 P00352 1/20 0.31
L3MBTL1 Q9Y468 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22175141 0.82 CTSS (0.47) CTSSCTSKPSENENCA2ALDH1A1
SCHEMBL3058032 0.80 CYP2D6 (0.36) CYP2D6CA2
SCHEMBL8894619 0.78 ALDH1A1 (0.43) CA2ALDH1A1L3MBTL1
SCHEMBL8897716 0.78 CTSS (0.30) CTSSCTSK
SCHEMBL8708108 0.75 KMT2A (0.39) CTSSCTSKPSENENCYP2D6CA2
SCHEMBL5565244 0.73 CTSK (0.38) CTSSCTSKPSENENCYP2D6CA2
SCHEMBL27526872 0.73 NOS1 (0.37) CYP2D6CA2
SCHEMBL31512927 0.72 PSENEN (0.47) CTSSCTSKPSENENCA2ALDH1A1
SCHEMBL25453643 0.71 CTSK (0.46) CTSSCTSKPSENENCA2ALDH1A1
SCHEMBL23901566 0.71 CTSS (0.46) CTSSCTSKPSENENCA2ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5624897-A PARASITICIDES, NEMATOSIDES OF CYCLIC PEPTIDE LACTONES FOR VETERINARY MEDICINE BAYER AKTIENGESELLSCHAFT (DE) 1997-04-29 US disclosed