Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.45 |
| ▸ | GPR55 | Q9Y2T6 | 2/20 | 0.45 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.42 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.42 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8420941 | 0.96 | MEN1 (0.52) | MEN1KMT2AL3MBTL1NPSR1GPR55 | |
| SCHEMBL8423236 | 0.90 | MEN1 (0.48) | MEN1KMT2AL3MBTL1NPSR1GPR55 | |
| SCHEMBL8419334 | 0.88 | L3MBTL1 (0.47) | MEN1KMT2AL3MBTL1NPSR1GPR55 | |
| SCHEMBL8419910 | 0.88 | MCL1 (0.44) | MEN1KMT2AL3MBTL1NPSR1GPR55 | |
| SCHEMBL8419332 | 0.88 | ALDH1A1 (0.43) | MEN1KMT2AL3MBTL1NPSR1GPR55 | |
| SCHEMBL8896031 | 0.88 | CACNA1H (0.44) | MEN1KMT2AL3MBTL1NPSR1GPR55 | |
| SCHEMBL8419767 | 0.86 | ALDH1A1 (0.42) | MEN1KMT2AL3MBTL1NPSR1GPR55 | |
| SCHEMBL8419290 | 0.85 | CNR1 (0.48) | MEN1KMT2AL3MBTL1NPSR1GPR55 | |
| SCHEMBL8421502 | 0.85 | CNR1 (0.51) | MEN1KMT2AL3MBTL1NPSR1GPR55 | |
| SCHEMBL8423073 | 0.85 | STAT3 (0.48) | MEN1KMT2AL3MBTL1NPSR1GPR55 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5686470-A | 2, 3-substituted pyridines for the treatment of inflammation | WEIER RICHARD M (US) | 1997-11-11 | — | — | US | disclosed |