Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 4/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.47 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.47 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.46 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | HTT | P42858 | 2/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | STAT3 | P40763 | 2/20 | 0.42 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.42 |
| ▸ | TUBB | P07437 | 1/20 | 0.42 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.42 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.42 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.42 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.42 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8894050 | 0.96 | MEN1 (0.48) | MEN1KMT2AL3MBTL1NPSR1GPR55 | |
| SCHEMBL8419334 | 0.92 | L3MBTL1 (0.47) | MEN1KMT2AL3MBTL1NPSR1GPR55 | |
| SCHEMBL8419332 | 0.92 | ALDH1A1 (0.43) | MEN1KMT2AL3MBTL1NPSR1GPR55 | |
| SCHEMBL8423236 | 0.92 | MEN1 (0.48) | MEN1KMT2AL3MBTL1NPSR1GPR55 | |
| SCHEMBL8419767 | 0.90 | ALDH1A1 (0.42) | MEN1KMT2AL3MBTL1NPSR1GPR55 | |
| SCHEMBL8419910 | 0.90 | MCL1 (0.44) | MEN1KMT2AL3MBTL1NPSR1GPR55 | |
| SCHEMBL8896031 | 0.89 | CACNA1H (0.44) | MEN1KMT2AL3MBTL1NPSR1GPR55 | |
| SCHEMBL8419297 | 0.88 | TUBB4A (0.47) | MEN1KMT2ANPSR1PTGS1PTGS2 | |
| SCHEMBL8423218 | 0.87 | HTT (0.50) | MEN1KMT2ANPSR1KDM4EALDH1A1 | |
| SCHEMBL8421502 | 0.87 | CNR1 (0.51) | MEN1KMT2AL3MBTL1NPSR1GPR55 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5916905-A | ANTIARTHRITIC AGENTS; ANALGESICS; ANTIPYRETICS | G. D. SEARLE & CO. (US) | 1999-06-29 | — | — | US | disclosed |
| US-5686470-A | 2, 3-substituted pyridines for the treatment of inflammation | WEIER RICHARD M (US) | 1997-11-11 | — | — | US | disclosed |