Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAS2R38 | P59533 | 2/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.49 |
| ▸ | MAPT | P10636 | 2/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8164721 | 0.86 | GAA (0.49) | TAS2R38SMN1; SMN2MAPTHTTCYP1A2 | |
| SCHEMBL622887 | 0.81 | MAPT (0.54) | TAS2R38SMN1; SMN2MAPTHTTCYP1A2 | |
| SCHEMBL17596668 | 0.79 | MAPT (0.55) | TAS2R38SMN1; SMN2MAPTHTTCYP1A2 | |
| SCHEMBL23618280 | 0.77 | ALDH1A1 (0.61) | TAS2R38SMN1; SMN2MAPTCYP1A2GAA | |
| SCHEMBL5448016 | 0.77 | ALDH1A1 (0.61) | TAS2R38SMN1; SMN2MAPTCYP1A2GAA | |
| SCHEMBL7743067 | 0.76 | LMNA (0.47) | TAS2R38SMN1; SMN2MAPTHTTCYP1A2 | |
| SCHEMBL10470753 | 0.75 | KMT2A (0.49) | MAPTKDM4ELMNAALDH1A1 | |
| SCHEMBL10670402 | 0.73 | MEN1 (0.67) | TAS2R38SMN1; SMN2MAPTCYP1A2GAA | |
| SCHEMBL5450589 | 0.72 | SMN1; SMN2 (0.71) | SMN1; SMN2MAPTHTTHPGDLMNA | |
| SCHEMBL10394940 | 0.72 | LMNA (0.66) | TAS2R38SMN1; SMN2MAPTHTTCYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2455098-A1 | New cyclic peptide compounds | Astellas Pharma Inc. (JP) | 2012-05-23 | — | — | EP | disclosed |