Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 5/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.37 |
| ▸ | TSHR | P16473 | 3/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.37 |
| ▸ | KLK7 | P49862 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.36 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.36 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.36 |
| ▸ | MDM4 | O15151 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.36 |
| ▸ | ALKBH1 | Q13686 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8897426 | 0.89 | CYP1A2 (0.39) | HCAR2LMNAALDH1A1TSHRCYP1A2 | |
| SCHEMBL8896106 | 0.88 | NAAA (0.42) | LMNAALDH1A1TSHRCYP1A2CYP3A4 | |
| SCHEMBL3482805 | 0.83 | HCAR2 (0.56) | HCAR2LMNAALDH1A1KLK7POLB | |
| SCHEMBL3482702 | 0.83 | HCAR2 (0.56) | HCAR2LMNAALDH1A1KLK7POLB | |
| SCHEMBL8894006 | 0.83 | HCAR2 (0.59) | HCAR2ALDH1A1TSHRCYP1A2CYP3A4 | |
| SCHEMBL8895848 | 0.82 | HCAR2 (0.42) | HCAR2LMNAALDH1A1KLK7POLB | |
| SCHEMBL1371364 | 0.81 | THRB (0.41) | HCAR2LMNAALDH1A1KLK7POLB | |
| SCHEMBL8895942 | 0.80 | ALDH1A1 (0.39) | LMNAALDH1A1TSHRCYP1A2CYP3A4 | |
| SCHEMBL3482642 | 0.79 | HCAR2 (0.64) | HCAR2LMNAALDH1A1TSHRCYP3A4 | |
| SCHEMBL17844649 | 0.79 | THRB (0.41) | HCAR2LMNAALDH1A1KLK7POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5670563-A | ORGANOTIN COMPOUND, PHOSPHORUS COMPOUND | CIBA-SPECIALTY CHEMICALS CORPORATION (US) | 1997-09-23 | — | — | US | disclosed |