Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 2/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | GRK2 | P25098 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | EGFR | P00533 | 2/20 | 0.44 |
| ▸ | ERBB2 | P04626 | 2/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | UTS2R | Q9UKP6 | 1/20 | 0.41 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.41 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.41 |
| ▸ | S1PR1 | P21453 | 4/20 | 0.40 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8895679 | 1.00 | IDO1 (0.49) | IDO1POLBGRK2KMT2AEGFR | |
| SCHEMBL8895471 | 0.95 | NPSR1 (0.44) | IDO1ALDH1A1CYP1A2CYP3A4CYP2C9 | |
| SCHEMBL8895500 | 0.91 | IDO1 (0.50) | IDO1POLBRAB9AALDH1A1NPSR1 | |
| SCHEMBL8897619 | 0.91 | IDO1 (0.50) | IDO1POLBKMT2AEGFRERBB2 | |
| SCHEMBL8896474 | 0.91 | ADAMTS5 (0.49) | ALDH1A1S1PR1ADAMTS5MMP2 | |
| SCHEMBL8895989 | 0.91 | UTS2R (0.51) | KMT2AEGFRERBB2ALDH1A1CYP1A2 | |
| SCHEMBL8897821 | 0.90 | S1PR1 (0.49) | EGFRERBB2ALDH1A1CYP1A2CYP3A4 | |
| SCHEMBL8895761 | 0.90 | ALDH1A1 (0.49) | POLBKMT2AEGFRERBB2ALDH1A1 | |
| SCHEMBL8896968 | 0.90 | S1PR1 (0.49) | EGFRERBB2ALDH1A1CYP1A2CYP3A4 | |
| SCHEMBL8896324 | 0.90 | IDO1 (0.49) | IDO1POLBEGFRERBB2RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5597848-A | PLATELET AGGREGATION INHIBITORS, ANTITHROMBOTIC AGENTS, ANTIASTHMATIC AGENTS, ANTIALLERGIC AGENTS | HOKURIKU SEIYAKU CO., LTD. (JP) | 1997-01-28 | — | — | US | disclosed |
| EP-0663392-A1 | BENZENESULFONAMIDE DERIVATIVE AND USE THEREOF | HOKURIKU SEIYAKU CO., LTD. (JP) | 1995-07-19 | — | — | EP | disclosed |