Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 2/20 | 0.50 |
| ▸ | MMP2 | P08253 | 5/20 | 0.49 |
| ▸ | MMP9 | P14780 | 4/20 | 0.49 |
| ▸ | MMP1 | P03956 | 3/20 | 0.49 |
| ▸ | MMP3 | P08254 | 3/20 | 0.49 |
| ▸ | MMP7 | P09237 | 3/20 | 0.49 |
| ▸ | MMP13 | P45452 | 3/20 | 0.49 |
| ▸ | CTSL | P07711 | 2/20 | 0.47 |
| ▸ | CTSS | P25774 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | ATM | Q13315 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | PLAAT3 | P53816 | 1/20 | 0.44 |
| ▸ | PLAAT5 | Q96KN8 | 1/20 | 0.44 |
| ▸ | PLAAT2 | Q9NWW9 | 1/20 | 0.44 |
| ▸ | PLAAT4 | Q9UL19 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8895584 | 0.93 | ALDH1A1 (0.46) | MMP2MMP9MMP7MMP13ALDH1A1 | |
| SCHEMBL8897619 | 0.92 | IDO1 (0.50) | IDO1MMP2MMP9MMP1MMP3 | |
| SCHEMBL8895380 | 0.92 | IDO1 (0.50) | IDO1MMP2MMP9MMP1MMP3 | |
| SCHEMBL8895679 | 0.91 | IDO1 (0.49) | IDO1MMP2ALDH1A1NPSR1RAB9A | |
| SCHEMBL8896324 | 0.91 | IDO1 (0.49) | IDO1MMP2MMP9MMP1MMP3 | |
| SCHEMBL8894878 | 0.91 | IDO1 (0.49) | IDO1MMP2ALDH1A1NPSR1RAB9A | |
| SCHEMBL8894760 | 0.91 | ALDH1A1 (0.48) | MMP9CTSLALDH1A1ATML3MBTL1 | |
| SCHEMBL8895597 | 0.90 | ALDH1A1 (0.53) | MMP2MMP9MMP1MMP3MMP13 | |
| SCHEMBL8896413 | 0.90 | ALDH1A1 (0.45) | MMP2MMP9ALDH1A1ATML3MBTL1 | |
| SCHEMBL8896474 | 0.90 | ADAMTS5 (0.49) | MMP2ALDH1A1ATML3MBTL1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5597848-A | PLATELET AGGREGATION INHIBITORS, ANTITHROMBOTIC AGENTS, ANTIASTHMATIC AGENTS, ANTIALLERGIC AGENTS | HOKURIKU SEIYAKU CO., LTD. (JP) | 1997-01-28 | — | — | US | disclosed |
| EP-0663392-A1 | BENZENESULFONAMIDE DERIVATIVE AND USE THEREOF | HOKURIKU SEIYAKU CO., LTD. (JP) | 1995-07-19 | — | — | EP | disclosed |