Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.41 |
| ▸ | GPR88 | Q9GZN0 | 2/20 | 0.38 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.38 |
| ▸ | PPARG | P37231 | 3/20 | 0.37 |
| ▸ | PPARA | Q07869 | 3/20 | 0.37 |
| ▸ | POLB | P06746 | 2/20 | 0.37 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.37 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.37 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.37 |
| ▸ | MDM4 | O15151 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8895848 | 0.87 | HCAR2 (0.42) | HCAR2POLBPABPC1APOBEC3AAPOBEC3G | |
| SCHEMBL3171202 | 0.86 | THRB (0.40) | HCAR2GPR88AOC3PPARGPPARA | |
| SCHEMBL8897426 | 0.84 | CYP1A2 (0.39) | HCAR2GPR88AOC3PPARGPPARA | |
| SCHEMBL9420058 | 0.84 | HCAR2 (0.60) | HCAR2MDM4LMNAMAPTMDM2 | |
| SCHEMBL9419971 | 0.84 | HCAR2 (0.60) | HCAR2MDM4LMNAMAPTMDM2 | |
| SCHEMBL9419967 | 0.84 | HCAR2 (0.60) | HCAR2MDM4LMNAMAPTMDM2 | |
| SCHEMBL11212738 | 0.83 | AOC3 (0.44) | AOC3PPARGPPARAPOLB | |
| SCHEMBL982155 | 0.83 | MTNR1A (0.43) | GPR88AOC3PPARGPPARAPOLB | |
| SCHEMBL1841218 | 0.83 | AOC3 (0.42) | GPR88AOC3PPARGPPARAPOLB | |
| SCHEMBL29377527 | 0.81 | PABPC1 (0.52) | AOC3PPARGPPARAPOLBPABPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5670563-A | ORGANOTIN COMPOUND, PHOSPHORUS COMPOUND | CIBA-SPECIALTY CHEMICALS CORPORATION (US) | 1997-09-23 | — | — | US | disclosed |