Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 1/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | GRK2 | P25098 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | EGFR | P00533 | 2/20 | 0.46 |
| ▸ | ERBB2 | P04626 | 2/20 | 0.46 |
| ▸ | TBXA2R | P21731 | 5/20 | 0.46 |
| ▸ | TBXAS1 | P24557 | 3/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | MMP2 | P08253 | 3/20 | 0.43 |
| ▸ | ADAMTS5 | Q9UNA0 | 1/20 | 0.43 |
| ▸ | MMP1 | P03956 | 1/20 | 0.43 |
| ▸ | MMP3 | P08254 | 1/20 | 0.43 |
| ▸ | MMP7 | P09237 | 1/20 | 0.43 |
| ▸ | MMP9 | P14780 | 1/20 | 0.43 |
| ▸ | MMP13 | P45452 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | ATM | Q13315 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8898502 | 1.00 | IDO1 (0.49) | IDO1NPSR1POLBGRK2KMT2A | |
| SCHEMBL8896354 | 0.95 | NPSR1 (0.53) | NPSR1TBXA2RTBXAS1MMP2ADAMTS5 | |
| SCHEMBL8894761 | 0.92 | ADAMTS5 (0.53) | NPSR1TBXA2RTBXAS1MMP2ADAMTS5 | |
| SCHEMBL8895531 | 0.92 | MMP2 (0.53) | IDO1NPSR1POLBMMP2MMP1 | |
| SCHEMBL8895361 | 0.90 | UTS2R (0.53) | NPSR1KMT2AEGFRERBB2TBXA2R | |
| SCHEMBL8895641 | 0.90 | IDO1 (0.49) | IDO1NPSR1POLBEGFRERBB2 | |
| SCHEMBL8898142 | 0.90 | S1PR1 (0.49) | NPSR1EGFRERBB2TBXA2RTBXAS1 | |
| SCHEMBL8895461 | 0.90 | S1PR1 (0.49) | NPSR1EGFRERBB2TBXA2RTBXAS1 | |
| SCHEMBL8896314 | 0.90 | ALDH1A1 (0.51) | IDO1NPSR1POLBKMT2AEGFR | |
| SCHEMBL8894878 | 0.89 | IDO1 (0.49) | IDO1NPSR1POLBGRK2KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5597848-A | PLATELET AGGREGATION INHIBITORS, ANTITHROMBOTIC AGENTS, ANTIASTHMATIC AGENTS, ANTIALLERGIC AGENTS | HOKURIKU SEIYAKU CO., LTD. (JP) | 1997-01-28 | — | — | US | disclosed |
| EP-0663392-A1 | BENZENESULFONAMIDE DERIVATIVE AND USE THEREOF | HOKURIKU SEIYAKU CO., LTD. (JP) | 1995-07-19 | — | — | EP | disclosed |