Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.53 |
| ▸ | POLB | P06746 | 3/20 | 0.53 |
| ▸ | MMP2 | P08253 | 5/20 | 0.52 |
| ▸ | MMP9 | P14780 | 4/20 | 0.52 |
| ▸ | PLAAT3 | P53816 | 1/20 | 0.49 |
| ▸ | PLAAT5 | Q96KN8 | 1/20 | 0.49 |
| ▸ | PLAAT2 | Q9NWW9 | 1/20 | 0.49 |
| ▸ | PLAAT4 | Q9UL19 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | MMP1 | P03956 | 3/20 | 0.46 |
| ▸ | MMP3 | P08254 | 2/20 | 0.46 |
| ▸ | PDE4A | P27815 | 2/20 | 0.46 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.46 |
| ▸ | PDE4C | Q08493 | 2/20 | 0.46 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.46 |
| ▸ | MMP13 | P45452 | 2/20 | 0.46 |
| ▸ | MMP8 | P22894 | 1/20 | 0.45 |
| ▸ | MMP14 | P50281 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8896997 | 0.93 | ALDH1A1 (0.54) | ALDH1A1POLBMMP2MMP9PLAAT3 | |
| SCHEMBL8895584 | 0.93 | ALDH1A1 (0.46) | ALDH1A1POLBMMP2MMP9MMP13 | |
| SCHEMBL8895761 | 0.91 | ALDH1A1 (0.49) | ALDH1A1POLBMMP2MMP9KMT2A | |
| SCHEMBL8894760 | 0.91 | ALDH1A1 (0.48) | ALDH1A1MMP9PLAAT3PLAAT5PLAAT2 | |
| SCHEMBL8895500 | 0.90 | IDO1 (0.50) | ALDH1A1POLBMMP2MMP9PLAAT3 | |
| SCHEMBL8896474 | 0.90 | ADAMTS5 (0.49) | ALDH1A1MMP2 | |
| SCHEMBL8896413 | 0.90 | ALDH1A1 (0.45) | ALDH1A1MMP2MMP9KMT2AMMP8 | |
| SCHEMBL8896241 | 0.87 | ADAMTS5 (0.48) | ALDH1A1MMP2 | |
| SCHEMBL8895471 | 0.85 | NPSR1 (0.44) | ALDH1A1MMP2 | |
| SCHEMBL8896373 | 0.85 | ALDH1A1 (0.49) | ALDH1A1POLBMMP2MMP9MMP13 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5597848-A | PLATELET AGGREGATION INHIBITORS, ANTITHROMBOTIC AGENTS, ANTIASTHMATIC AGENTS, ANTIALLERGIC AGENTS | HOKURIKU SEIYAKU CO., LTD. (JP) | 1997-01-28 | — | — | US | disclosed |
| EP-0663392-A1 | BENZENESULFONAMIDE DERIVATIVE AND USE THEREOF | HOKURIKU SEIYAKU CO., LTD. (JP) | 1995-07-19 | — | — | EP | disclosed |