Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.46 |
| ▸ | ATM | Q13315 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.45 |
| ▸ | CA12 | O43570 | 1/20 | 0.44 |
| ▸ | CA7 | P43166 | 1/20 | 0.44 |
| ▸ | CA9 | Q16790 | 1/20 | 0.44 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.44 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.44 |
| ▸ | MMP2 | P08253 | 6/20 | 0.42 |
| ▸ | MMP9 | P14780 | 5/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | ADAMTS4 | O75173 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | MMP7 | P09237 | 1/20 | 0.41 |
| ▸ | MMP8 | P22894 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8894760 | 0.94 | ALDH1A1 (0.48) | ALDH1A1ATML3MBTL1NPSR1CA7 | |
| SCHEMBL8895597 | 0.93 | ALDH1A1 (0.53) | ALDH1A1MMP2MMP9MMP8MMP13 | |
| SCHEMBL8896413 | 0.93 | ALDH1A1 (0.45) | ALDH1A1ATML3MBTL1NPSR1CA12 | |
| SCHEMBL8895500 | 0.93 | IDO1 (0.50) | ALDH1A1ATML3MBTL1NPSR1MMP2 | |
| SCHEMBL8896474 | 0.93 | ADAMTS5 (0.49) | ALDH1A1ATML3MBTL1MMP2GAA | |
| SCHEMBL8896323 | 0.90 | CTSL (0.45) | ALDH1A1NPSR1MAPTSMN1; SMN2 | |
| SCHEMBL8896241 | 0.90 | ADAMTS5 (0.48) | ALDH1A1ATML3MBTL1MMP2GAA | |
| SCHEMBL8895021 | 0.89 | NPSR1 (0.52) | ALDH1A1ATML3MBTL1NPSR1CYP1A2 | |
| SCHEMBL8895471 | 0.88 | NPSR1 (0.44) | ALDH1A1NPSR1CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL8894908 | 0.88 | CA12 (0.45) | ALDH1A1NPSR1CA12CA7CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5597848-A | PLATELET AGGREGATION INHIBITORS, ANTITHROMBOTIC AGENTS, ANTIASTHMATIC AGENTS, ANTIALLERGIC AGENTS | HOKURIKU SEIYAKU CO., LTD. (JP) | 1997-01-28 | — | — | US | disclosed |
| EP-0663392-A1 | BENZENESULFONAMIDE DERIVATIVE AND USE THEREOF | HOKURIKU SEIYAKU CO., LTD. (JP) | 1995-07-19 | — | — | EP | disclosed |