Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ASIC3 | Q9UHC3 | 1/20 | 0.35 |
| ▸ | F10 | P00742 | 3/20 | 0.33 |
| ▸ | HTR6 | P50406 | 3/20 | 0.32 |
| ▸ | DRD2 | P14416 | 1/20 | 0.32 |
| ▸ | HTR2A | P28223 | 1/20 | 0.32 |
| ▸ | HTR2C | P28335 | 1/20 | 0.32 |
| ▸ | DRD3 | P35462 | 1/20 | 0.32 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.31 |
| ▸ | IDO1 | P14902 | 1/20 | 0.31 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.30 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8561653 | 0.95 | ASIC3 (0.35) | ASIC3HTR6DRD2HTR2AHTR2C | |
| SCHEMBL8896083 | 0.84 | ASIC3 (0.34) | ASIC3F10HTR6ROCK2HRH3 | |
| SCHEMBL8563370 | 0.80 | ASIC3 (0.40) | ASIC3F10HTR6ROCK2HRH3 | |
| Acetic Acid SCHEMBL8895876 | 0.78 | ASIC3 (0.38) | ASIC3F10HTR6HRH3 | |
| SCHEMBL8985729 | 0.77 | ASIC3 (0.37) | ASIC3HTR6DRD2HTR2AHTR2C | |
| SCHEMBL8894590 | 0.76 | F10 (0.35) | ASIC3F10HTR6 | |
| SCHEMBL8563524 | 0.75 | ACHE (0.32) | ASIC3 | |
| SCHEMBL8559578 | 0.74 | HTR6 (0.42) | HTR6DRD2HTR2AHTR2CDRD3 | |
| Hydrochloric Acid SCHEMBL8566255 | 0.73 | HTR6 (0.41) | HTR6DRD2HTR2AHTR2CDRD3 | |
| SCHEMBL19642967 | 0.73 | PLAU (0.49) | ASIC3HTR6DRD2HTR2AHTR2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5612335-A | ANTICOAGULANTS; COMBATING/PREVENTING DISEASES WHERE CELL AGGREGATES OCCUR OR CELL-MATRIX INTERACTIONS PLAY A PART | KARL THOMAE GMBH (DE) | 1997-03-18 | — | — | US | disclosed |
| US-5519036-A | IMIDAZOLIDINONES, ANTICOAGULANTS, CELL AGGREGATION PREVENTION | KARL THOMAE GMBH (DE) | 1996-05-21 | — | — | US | disclosed |