Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABHD6 | Q9BV23 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.47 |
| ▸ | MEN1 | O00255 | 3/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | ACE | P12821 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.45 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.45 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
| ▸ | CASP1 | P29466 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | MMP8 | P22894 | 1/20 | 0.43 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | PRMT5 | O14744 | 3/20 | 0.43 |
| ▸ | WDR77 | Q9BQA1 | 3/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8610388 | 0.85 | ABHD6 (0.56) | ABHD6KMT2AMEN1MAPTACE | |
| SCHEMBL8896159 | 0.83 | ACE (0.45) | KMT2AMEN1MAPTL3MBTL1ACE | |
| SCHEMBL8898654 | 0.83 | ACE (0.45) | KMT2AMEN1MAPTL3MBTL1ACE | |
| SCHEMBL8895893 | 0.77 | RECQL (0.52) | ABHD6KMT2AMEN1MAPTL3MBTL1 | |
| SCHEMBL6102363 | 0.75 | ABHD6 (0.68) | ABHD6KMT2AMEN1MAPTACE | |
| SCHEMBL8896829 | 0.74 | PPARG (0.48) | KMT2AMEN1ALDH1A1NPC1SMN1; SMN2 | |
| SCHEMBL11980686 | 0.74 | ABHD6 (0.66) | ABHD6KMT2AMEN1MAPTACE | |
| SCHEMBL324836 | 0.73 | PRMT5 (0.55) | ABHD6KMT2AMEN1MAPTALDH1A1 | |
| SCHEMBL7454462 | 0.73 | ABHD6 (0.61) | ABHD6KMT2AMEN1MAPTACE | |
| SCHEMBL4952073 | 0.71 | HDAC8 (0.74) | KMT2AMEN1ACEALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5656604-A | HYPOTENSIVE AGENT; ENDOTHELIN ANTAGONIST | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1997-08-12 | — | — | US | disclosed |