Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 5/20 | 0.48 |
| ▸ | PPARA | Q07869 | 4/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5186555 | 0.84 | SMN1; SMN2 (0.46) | SMN1; SMN2MEN1HTTKMT2AHPGD | |
| SCHEMBL8897285 | 0.78 | PPARG (0.45) | PPARGPPARASMN1; SMN2MEN1HTT | |
| SCHEMBL8896159 | 0.78 | ACE (0.45) | PPARGPPARASMN1; SMN2MEN1KMT2A | |
| SCHEMBL8898654 | 0.78 | ACE (0.45) | PPARGPPARASMN1; SMN2MEN1KMT2A | |
| SCHEMBL8897280 | 0.78 | PPARG (0.45) | PPARGPPARASMN1; SMN2MEN1HTT | |
| SCHEMBL27620542 | 0.77 | TSHR (0.56) | SMN1; SMN2MEN1HTTKMT2AHPGD | |
| SCHEMBL21978418 | 0.75 | SRR (0.62) | PPARGPPARA | |
| SCHEMBL8897470 | 0.75 | CTSL (0.43) | SMN1; SMN2MEN1HTTKMT2AHPGD | |
| SCHEMBL8897474 | 0.75 | PPARG (0.36) | PPARGPPARASMN1; SMN2MEN1HTT | |
| SCHEMBL5186550 | 0.75 | ALDH1A1 (0.50) | SMN1; SMN2MEN1HTTKMT2AHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5656604-A | HYPOTENSIVE AGENT; ENDOTHELIN ANTAGONIST | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1997-08-12 | — | — | US | disclosed |