Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACE | P12821 | 6/20 | 0.45 |
| ▸ | NPC1 | O15118 | 2/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | MMP13 | P45452 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | PPARG | P37231 | 1/20 | 0.39 |
| ▸ | PPARA | Q07869 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8898654 | 1.00 | ACE (0.45) | ACENPC1TDP1MMP13L3MBTL1 | |
| SCHEMBL8895899 | 0.83 | ABHD6 (0.49) | ACENPC1L3MBTL1GAAALDH1A1 | |
| SCHEMBL8895815 | 0.80 | DPP4 (0.45) | ACEMMP13ALDH1A1MAPTMEN1 | |
| SCHEMBL8895820 | 0.80 | ACE (0.41) | ACENPC1MMP13GAAALDH1A1 | |
| SCHEMBL9359097 | 0.79 | SRR (0.51) | ACENPC1TDP1GAAMEN1 | |
| SCHEMBL8909660 | 0.79 | SRR (0.51) | ACENPC1TDP1GAAMEN1 | |
| SCHEMBL8682156 | 0.79 | SRR (0.51) | ACENPC1TDP1GAAMEN1 | |
| SCHEMBL8896829 | 0.78 | PPARG (0.48) | NPC1ALDH1A1MEN1TSHRKMT2A | |
| SCHEMBL8610410 | 0.76 | FOLH1 (0.40) | ALDH1A1MEN1KMT2AHPGD | |
| SCHEMBL8608851 | 0.76 | FOLH1 (0.40) | ALDH1A1MEN1KMT2AHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5656604-A | HYPOTENSIVE AGENT; ENDOTHELIN ANTAGONIST | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1997-08-12 | — | — | US | disclosed |