Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP8 | P22894 | 1/20 | 0.49 |
| ▸ | ABHD6 | Q9BV23 | 1/20 | 0.47 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.46 |
| ▸ | ACE | P12821 | 2/20 | 0.46 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.44 |
| ▸ | PRMT5 | O14744 | 3/20 | 0.43 |
| ▸ | WDR77 | Q9BQA1 | 3/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.43 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8896167 | 0.84 | GPR119 (0.43) | ALDH1A1TDP1KMT2AMEN1 | |
| SCHEMBL8896841 | 0.73 | ALDH1A1 (0.40) | ALDH1A1MAPTKMT2AMEN1 | |
| SCHEMBL1202402 | 0.73 | ESR2 (0.70) | ABHD6NOTUMPRMT5WDR77ALDH1A1 | |
| SCHEMBL29369046 | 0.73 | ESR2 (0.70) | ABHD6NOTUMPRMT5WDR77ALDH1A1 | |
| SCHEMBL15355424 | 0.72 | PRMT5 (0.67) | ABHD6ACENOTUMPRMT5WDR77 | |
| Ammonia Solution, Strong SCHEMBL30461763 | 0.72 | ESR2 (0.68) | ABHD6NOTUMPRMT5WDR77ALDH1A1 | |
| SCHEMBL324228 | 0.71 | TMEM97 (0.67) | PRMT5WDR77HRH3KMT2AMEN1 | |
| SCHEMBL6102363 | 0.70 | ABHD6 (0.68) | ABHD6ACENOTUMPRMT5WDR77 | |
| SCHEMBL8610388 | 0.70 | ABHD6 (0.56) | ABHD6HDAC8ACEKDM4ENOTUM | |
| SCHEMBL8895893 | 0.70 | RECQL (0.52) | ABHD6HDAC8ACEPRMT5WDR77 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5656604-A | HYPOTENSIVE AGENT; ENDOTHELIN ANTAGONIST | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1997-08-12 | — | — | US | disclosed |